Improved performance of sequence search approaches in remote homology detection [v2; ref status: indexed, http://f1000r.es/3qo]
The protein sequence space is vast and diverse, spanning across different families. Biologically meaningful relationships exist between proteins at superfamily level. However, it is highly challenging to establish convincing relationships at the superfamily level by means of simple sequence searches...
Main Authors: | Adwait Govind Joshi, Upadhyayula Surya Raghavender, Ramanathan Sowdhamini |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2014-07-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/2-93/v2 |
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