A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
Abstract Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Aging Medicine |
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| Online Access: | https://doi.org/10.1002/agm2.12216 |
| _version_ | 1811242094421868544 |
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| author | Faizan Ahmad Punya Sachdeva |
| author_facet | Faizan Ahmad Punya Sachdeva |
| author_sort | Faizan Ahmad |
| collection | DOAJ |
| description | Abstract Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So in this review, we are focusing on stem cell therapy for AD. This review will cover all stem cells like mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, and neural stem cells. Clinical trials of AD have also been discussed. Finally, limitations of stem cells are discussed with ongoing clinical trials, and in the future stem cell therapy can be used for treatment of AD. |
| first_indexed | 2024-04-12T13:46:00Z |
| format | Article |
| id | doaj.art-bd378f68f7024b55bdbe1e2be7cd717c |
| institution | Directory Open Access Journal |
| issn | 2475-0360 |
| language | English |
| last_indexed | 2024-04-12T13:46:00Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Aging Medicine |
| spelling | doaj.art-bd378f68f7024b55bdbe1e2be7cd717c2022-12-22T03:30:40ZengWileyAging Medicine2475-03602022-09-015318219010.1002/agm2.12216A consolidated review on stem cell therapy for treatment and management of Alzheimer's diseaseFaizan Ahmad0Punya Sachdeva1Department of Medical Elementology and Toxicology Jamia Hamdard University Delhi IndiaAmity Institute of Neuropsychology and Neurosciences Amity University Noida Uttar Pradesh IndiaAbstract Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So in this review, we are focusing on stem cell therapy for AD. This review will cover all stem cells like mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, and neural stem cells. Clinical trials of AD have also been discussed. Finally, limitations of stem cells are discussed with ongoing clinical trials, and in the future stem cell therapy can be used for treatment of AD.https://doi.org/10.1002/agm2.12216Alzheimer's diseaseembryonic stem cellsInduced pluripotent stem cellsmesenchymal stem cellsneural stem cells |
| spellingShingle | Faizan Ahmad Punya Sachdeva A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease Aging Medicine Alzheimer's disease embryonic stem cells Induced pluripotent stem cells mesenchymal stem cells neural stem cells |
| title | A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease |
| title_full | A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease |
| title_fullStr | A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease |
| title_full_unstemmed | A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease |
| title_short | A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease |
| title_sort | consolidated review on stem cell therapy for treatment and management of alzheimer s disease |
| topic | Alzheimer's disease embryonic stem cells Induced pluripotent stem cells mesenchymal stem cells neural stem cells |
| url | https://doi.org/10.1002/agm2.12216 |
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