Mechanistic Insight into the Peptide Binding Modes to Two <i>M. tb</i> MazF Toxins

Mechanistic Insight into the Peptide Binding Modes to Two <i>M. tb</i> MazF Toxins

Tuberculosis (TB) is a contagious disease caused by <i>Mycobacterium tuberculosis</i> (<i>M. tb</i>). It is regarded as a major health threat all over the world, mainly because of its high mortality and drug-resistant nature. Toxin-antitoxin (TA) systems are modules ubiquitou...

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Bibliographic Details
Main Authors: Ran Chen, Jie Zhou, Wei Xie
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Toxins
Subjects:
tuberculosis
<i>Mycobacterium tuberculosis</i>
TA system
MazEF
antimicrobial peptide
cocrystal structure
Online Access:https://www.mdpi.com/2072-6651/13/5/319

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