Marfan syndrome
Marfan syndrome (MFS) is the autosomal dominant-inherited multisystem connective-tissue disorder, with a reported incidence of 1 in 10,000 individuals and equal distribution in both genders. The main clinical manifestation of this disorder consists of an exaggerated length of the upper and lower lim...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2017;volume=9;issue=1;spage=73;epage=77;aulast=Sivasankari |
| _version_ | 1818888641079934976 |
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| author | T Sivasankari Philips Mathew Ravi David Austin Sakthi Devi |
| author_facet | T Sivasankari Philips Mathew Ravi David Austin Sakthi Devi |
| author_sort | T Sivasankari |
| collection | DOAJ |
| description | Marfan syndrome (MFS) is the autosomal dominant-inherited multisystem connective-tissue disorder, with a reported incidence of 1 in 10,000 individuals and equal distribution in both genders. The main clinical manifestation of this disorder consists of an exaggerated length of the upper and lower limbs, hyperlaxity, scoliosis, alterations in the cardiovascular and pulmonary systems, and atypical bone overgrowth. Orofacial manifestations such as high-arched palate, hypodontia, long narrow teeth, bifid uvula, mandibular prognathism, and temporomandibular disorders are also common. Early diagnosis of MFS is essential to prevent the cardiovascular complications and treatment of orofacial manifestations, thus to increase the quality of life of the patient. |
| first_indexed | 2024-12-19T16:56:21Z |
| format | Article |
| id | doaj.art-bd3f1d7854e146d28d309c2c173aab75 |
| institution | Directory Open Access Journal |
| issn | 0975-7406 |
| language | English |
| last_indexed | 2024-12-19T16:56:21Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj.art-bd3f1d7854e146d28d309c2c173aab752022-12-21T20:13:25ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062017-01-0191737710.4103/jpbs.JPBS_326_16Marfan syndromeT SivasankariPhilips MathewRavi David AustinSakthi DeviMarfan syndrome (MFS) is the autosomal dominant-inherited multisystem connective-tissue disorder, with a reported incidence of 1 in 10,000 individuals and equal distribution in both genders. The main clinical manifestation of this disorder consists of an exaggerated length of the upper and lower limbs, hyperlaxity, scoliosis, alterations in the cardiovascular and pulmonary systems, and atypical bone overgrowth. Orofacial manifestations such as high-arched palate, hypodontia, long narrow teeth, bifid uvula, mandibular prognathism, and temporomandibular disorders are also common. Early diagnosis of MFS is essential to prevent the cardiovascular complications and treatment of orofacial manifestations, thus to increase the quality of life of the patient.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2017;volume=9;issue=1;spage=73;epage=77;aulast=SivasankariAutosomal dominantMarfan syndromeoral manifestation |
| spellingShingle | T Sivasankari Philips Mathew Ravi David Austin Sakthi Devi Marfan syndrome Journal of Pharmacy and Bioallied Sciences Autosomal dominant Marfan syndrome oral manifestation |
| title | Marfan syndrome |
| title_full | Marfan syndrome |
| title_fullStr | Marfan syndrome |
| title_full_unstemmed | Marfan syndrome |
| title_short | Marfan syndrome |
| title_sort | marfan syndrome |
| topic | Autosomal dominant Marfan syndrome oral manifestation |
| url | http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2017;volume=9;issue=1;spage=73;epage=77;aulast=Sivasankari |
| work_keys_str_mv | AT tsivasankari marfansyndrome AT philipsmathew marfansyndrome AT ravidavidaustin marfansyndrome AT sakthidevi marfansyndrome |