Bivalent System of Deoxyribozymes for Efficient RNA Cleavage

Bivalent System of Deoxyribozymes for Efficient RNA Cleavage

The goal of gene therapy is to treat diseases through gene editing and modification of gene expression. Viral vectors, antisense oligonucleotides (ASO) and RNA interference (RNAi) are some of the gene therapies under development. DNAzymes, or deoxyribozymes (Dzs), are simple in design tools for RNA-...

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Bibliographic Details
Main Authors: Michael Batsa, Mikhail V. Dubovichenko, Dmitry M. Kolpashchikov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biology and Life Sciences Forum
Subjects:
bivalent system
deoxyribozymes
DNAzymes
gene therapy
biomolecules
Online Access:https://www.mdpi.com/2673-9976/20/1/6

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