Oxime Esters of 2,6-Diazaanthracene-9,10-dione and 4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents

Oxime Esters of 2,6-Diazaanthracene-9,10-dione and 4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents

Two series of oxime esters containing the 2,6-diazaanthracene-9,10-dione bis-(O-benzoyloxime) and 4,5-diazafluoren-9-one O-9-benzoyloxime moieties have been synthesized and tested as photo-induced DNA cleaving agents. All these compounds were found to cleave DNA upon irradiation with 312 nm UV light...

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Bibliographic Details
Main Authors:	Shang-Shing P. Chou, Jui-Chi Juan, Shwu-Chen Tsay, Kuei Pin Huang, Jih Ru Hwu
Format:	Article
Language:	English
Published:	MDPI AG 2012-03-01
Series:	Molecules
Subjects:	photo-induced DNA-cleavage oxime esters 2,6-diazaanthracene-9,10-dione 4,5-diazafluoren-9-one
Online Access:	http://www.mdpi.com/1420-3049/17/3/3370/

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