Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review
Abstract Objective Anxiety and depression are common comorbidities in people living with epilepsy. Emerging research suggests that these conditions may even predate epilepsy onset. This review aimed to summarize the prevalence of clinically significant anxiety and depressive symptoms in people with...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Epilepsia Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/epi4.12766 |
| _version_ | 1797729188969447424 |
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| author | William Cronin Patrick Kwan Emma Foster |
| author_facet | William Cronin Patrick Kwan Emma Foster |
| author_sort | William Cronin |
| collection | DOAJ |
| description | Abstract Objective Anxiety and depression are common comorbidities in people living with epilepsy. Emerging research suggests that these conditions may even predate epilepsy onset. This review aimed to summarize the prevalence of clinically significant anxiety and depressive symptoms in people with first seizures and newly diagnosed epilepsy, as well as clinicodemographic factors associated with these symptoms. Methods A scoping literature review was performed. OVID Medline and Embase were searched from January 1, 2000, through May 1, 2022. Articles of interest were selected based on predetermined inclusion and exclusion criteria. Results From 1836 studies identified on screening, 16 met eligibility criteria and were included in the review. Clinically significant anxiety and depressive symptoms, as determined by validated cutoff scores for anxiety and depression screening instruments, were common in people with first seizures (range 13–28%) and newly diagnosed epilepsy (range 11–45%). They were associated with a range of clinicodemographic factors including past psychiatric history and trauma, personality traits, self‐esteem, and stigma profiles. Significance There is substantial evidence that clinically significant anxiety and depressive symptoms are often present at the time and shortly following the first seizure or epilepsy diagnosis. Future research is needed to better understand the complex interactions between these common psychiatric comorbidities, new‐onset seizure disorders, and certain clinicodemographic characteristics. This knowledge may inform targeted and holistic treatment approaches. |
| first_indexed | 2024-03-12T11:25:25Z |
| format | Article |
| id | doaj.art-bd4a501aa6224a6fa4ba912369886ca4 |
| institution | Directory Open Access Journal |
| issn | 2470-9239 |
| language | English |
| last_indexed | 2024-03-12T11:25:25Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Epilepsia Open |
| spelling | doaj.art-bd4a501aa6224a6fa4ba912369886ca42023-09-01T09:39:50ZengWileyEpilepsia Open2470-92392023-09-018375877210.1002/epi4.12766Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping reviewWilliam Cronin0Patrick Kwan1Emma Foster2Faculty of Medicine, Dentistry and Health Sciences University of Melbourne Victoria Parkville AustraliaNeurology Department Alfred Health Melbourne Victoria AustraliaNeurology Department Alfred Health Melbourne Victoria AustraliaAbstract Objective Anxiety and depression are common comorbidities in people living with epilepsy. Emerging research suggests that these conditions may even predate epilepsy onset. This review aimed to summarize the prevalence of clinically significant anxiety and depressive symptoms in people with first seizures and newly diagnosed epilepsy, as well as clinicodemographic factors associated with these symptoms. Methods A scoping literature review was performed. OVID Medline and Embase were searched from January 1, 2000, through May 1, 2022. Articles of interest were selected based on predetermined inclusion and exclusion criteria. Results From 1836 studies identified on screening, 16 met eligibility criteria and were included in the review. Clinically significant anxiety and depressive symptoms, as determined by validated cutoff scores for anxiety and depression screening instruments, were common in people with first seizures (range 13–28%) and newly diagnosed epilepsy (range 11–45%). They were associated with a range of clinicodemographic factors including past psychiatric history and trauma, personality traits, self‐esteem, and stigma profiles. Significance There is substantial evidence that clinically significant anxiety and depressive symptoms are often present at the time and shortly following the first seizure or epilepsy diagnosis. Future research is needed to better understand the complex interactions between these common psychiatric comorbidities, new‐onset seizure disorders, and certain clinicodemographic characteristics. This knowledge may inform targeted and holistic treatment approaches.https://doi.org/10.1002/epi4.12766anxiety disorderdepressionepilepsyfirst seizurepsychological screening |
| spellingShingle | William Cronin Patrick Kwan Emma Foster Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review Epilepsia Open anxiety disorder depression epilepsy first seizure psychological screening |
| title | Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review |
| title_full | Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review |
| title_fullStr | Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review |
| title_full_unstemmed | Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review |
| title_short | Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review |
| title_sort | anxiety and depressive symptoms in adults with new onset seizures a scoping review |
| topic | anxiety disorder depression epilepsy first seizure psychological screening |
| url | https://doi.org/10.1002/epi4.12766 |
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