Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss,
ABSTRACT INTRODUCTION: Several theories attempt to explain the pathophysiology of sudden hearing loss. OBJECTIVE: The objective of this study was to investigate the possible role of inflammation and atherothrombosis in sudden hearing loss patients through the neutrophil-to-lymphocyte ratio and m...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-12-01
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| Series: | Brazilian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000600636&lng=en&tlng=en |
| _version_ | 1818915029257289728 |
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| author | Rauf Oguzhan Kum Muge Ozcan Deniz Baklaci Nurcan Yurtsever Kum Yavuz Fuat Yilmaz Adnan Unal Yonca Avci |
| author_facet | Rauf Oguzhan Kum Muge Ozcan Deniz Baklaci Nurcan Yurtsever Kum Yavuz Fuat Yilmaz Adnan Unal Yonca Avci |
| author_sort | Rauf Oguzhan Kum |
| collection | DOAJ |
| description | ABSTRACT INTRODUCTION: Several theories attempt to explain the pathophysiology of sudden hearing loss. OBJECTIVE: The objective of this study was to investigate the possible role of inflammation and atherothrombosis in sudden hearing loss patients through the neutrophil-to-lymphocyte ratio and mean platelet volume. METHODS: Study design - retrospective cross-sectional historical cohort. This study was conducted on two groups: one with 59 individuals diagnosed with sudden hearing loss, and other with 59 healthy individuals with the same characteristics of gender and age distribution, neutrophil-to-lymphocyte ratio and mean platelet volume levels were measured in patients diagnosed with sudden hearing loss as well as in the control group, and it was verified whether these results interfered for a better or worse prognosis with treatment of sudden deafness. RESULTS: Neutrophil-to-lymphocyte ratio levels are much higher in patients diagnosed with sudden hearing loss compared to the control group. Similarly, mean levels of neutrophil-to-lymphocyte ratio are higher in non-recovered versus recovered patients (p = 0.001). However, we could not find a correlation with mean platelet volume levels (p > 0.05). CONCLUSION: Neutrophil-to-lymphocyte ratio is a quick and reliable indicator regarding diagnosis and prognosis of sudden hearing loss; on the other hand, mean platelet volume may be considered a less important indicator in this aspect. |
| first_indexed | 2024-12-19T23:55:47Z |
| format | Article |
| id | doaj.art-bd4c180385674ab0a2a2297379446ee7 |
| institution | Directory Open Access Journal |
| issn | 1808-8686 |
| language | English |
| last_indexed | 2024-12-19T23:55:47Z |
| publishDate | 2015-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Otorhinolaryngology |
| spelling | doaj.art-bd4c180385674ab0a2a2297379446ee72022-12-21T20:01:01ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86862015-12-0181663664110.1016/j.bjorl.2015.08.009S1808-86942015000600636Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss,Rauf Oguzhan KumMuge OzcanDeniz BaklaciNurcan Yurtsever KumYavuz Fuat YilmazAdnan UnalYonca AvciABSTRACT INTRODUCTION: Several theories attempt to explain the pathophysiology of sudden hearing loss. OBJECTIVE: The objective of this study was to investigate the possible role of inflammation and atherothrombosis in sudden hearing loss patients through the neutrophil-to-lymphocyte ratio and mean platelet volume. METHODS: Study design - retrospective cross-sectional historical cohort. This study was conducted on two groups: one with 59 individuals diagnosed with sudden hearing loss, and other with 59 healthy individuals with the same characteristics of gender and age distribution, neutrophil-to-lymphocyte ratio and mean platelet volume levels were measured in patients diagnosed with sudden hearing loss as well as in the control group, and it was verified whether these results interfered for a better or worse prognosis with treatment of sudden deafness. RESULTS: Neutrophil-to-lymphocyte ratio levels are much higher in patients diagnosed with sudden hearing loss compared to the control group. Similarly, mean levels of neutrophil-to-lymphocyte ratio are higher in non-recovered versus recovered patients (p = 0.001). However, we could not find a correlation with mean platelet volume levels (p > 0.05). CONCLUSION: Neutrophil-to-lymphocyte ratio is a quick and reliable indicator regarding diagnosis and prognosis of sudden hearing loss; on the other hand, mean platelet volume may be considered a less important indicator in this aspect.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000600636&lng=en&tlng=enPerda auditiva neurossensorialPerda auditiva súbitaNeutrófilosPlaquetasMarcadores biológicosLinfócitos |
| spellingShingle | Rauf Oguzhan Kum Muge Ozcan Deniz Baklaci Nurcan Yurtsever Kum Yavuz Fuat Yilmaz Adnan Unal Yonca Avci Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, Brazilian Journal of Otorhinolaryngology Perda auditiva neurossensorial Perda auditiva súbita Neutrófilos Plaquetas Marcadores biológicos Linfócitos |
| title | Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, |
| title_full | Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, |
| title_fullStr | Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, |
| title_full_unstemmed | Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, |
| title_short | Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss, |
| title_sort | investigation of neutrophil to lymphocyte ratio and mean platelet volume in sudden hearing loss |
| topic | Perda auditiva neurossensorial Perda auditiva súbita Neutrófilos Plaquetas Marcadores biológicos Linfócitos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000600636&lng=en&tlng=en |
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