Requirements for diploid allogenic cell lines used for regenerative medicine
Cell transplantation becomes a mode of correcting the functional failure of organs and tissues in injury and a number of diseases. The paper considers the issues concerning the biological safety of therapy with differential cells: in vitro cultured fibroblasts. The Russian line M-22 derived from the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
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| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/252 |
| _version_ | 1826564629190410240 |
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| author | O. I. Konyushko B. V. Khvatov S. V. Smirnov V. S. Bocharova |
| author_facet | O. I. Konyushko B. V. Khvatov S. V. Smirnov V. S. Bocharova |
| author_sort | O. I. Konyushko |
| collection | DOAJ |
| description | Cell transplantation becomes a mode of correcting the functional failure of organs and tissues in injury and a number of diseases. The paper considers the issues concerning the biological safety of therapy with differential cells: in vitro cultured fibroblasts. The Russian line M-22 derived from the skin and muscle of diploid human embryonic cells has persisted just for more than 40 years and successfully used to treat patients with severe burns. |
| first_indexed | 2024-03-12T04:56:06Z |
| format | Article |
| id | doaj.art-bd4cc2db375d4df897ca8226e755b28a |
| institution | Directory Open Access Journal |
| issn | 2074-0506 2542-0909 |
| language | English |
| last_indexed | 2025-03-14T10:22:54Z |
| publishDate | 2018-08-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj.art-bd4cc2db375d4df897ca8226e755b28a2025-03-02T11:07:32ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0102313410.23873/2074-0506-2009-0-2-31-34241Requirements for diploid allogenic cell lines used for regenerative medicineO. I. Konyushko0B. V. Khvatov1S. V. Smirnov2V. S. Bocharova3N.V. Sklifosovsky Research Institute of Emergency CareN.V. Sklifosovsky Research Institute of Emergency CareN.V. Sklifosovsky Research Institute of Emergency CareN.V. Sklifosovsky Research Institute of Emergency CareCell transplantation becomes a mode of correcting the functional failure of organs and tissues in injury and a number of diseases. The paper considers the issues concerning the biological safety of therapy with differential cells: in vitro cultured fibroblasts. The Russian line M-22 derived from the skin and muscle of diploid human embryonic cells has persisted just for more than 40 years and successfully used to treat patients with severe burns.https://www.jtransplantologiya.ru/jour/article/view/252stem cell transplantationbiological safetydiploid cell line |
| spellingShingle | O. I. Konyushko B. V. Khvatov S. V. Smirnov V. S. Bocharova Requirements for diploid allogenic cell lines used for regenerative medicine Трансплантология (Москва) stem cell transplantation biological safety diploid cell line |
| title | Requirements for diploid allogenic cell lines used for regenerative medicine |
| title_full | Requirements for diploid allogenic cell lines used for regenerative medicine |
| title_fullStr | Requirements for diploid allogenic cell lines used for regenerative medicine |
| title_full_unstemmed | Requirements for diploid allogenic cell lines used for regenerative medicine |
| title_short | Requirements for diploid allogenic cell lines used for regenerative medicine |
| title_sort | requirements for diploid allogenic cell lines used for regenerative medicine |
| topic | stem cell transplantation biological safety diploid cell line |
| url | https://www.jtransplantologiya.ru/jour/article/view/252 |
| work_keys_str_mv | AT oikonyushko requirementsfordiploidallogeniccelllinesusedforregenerativemedicine AT bvkhvatov requirementsfordiploidallogeniccelllinesusedforregenerativemedicine AT svsmirnov requirementsfordiploidallogeniccelllinesusedforregenerativemedicine AT vsbocharova requirementsfordiploidallogeniccelllinesusedforregenerativemedicine |