Results of a control quality strategy in cervical cytology
OBJECTIVE: To determine the efficacy of a quality control strategy in cervical cytology in the detection of high-grade squamous intraepithelial lesions. METHODS: Forty-two patients were selected who underwent a Pap smear and cervical uterine biopsy between April 2008 and December 2009, with evidence...
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2012-03-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082012000100018&tlng=en |
| _version_ | 1818978841046024192 |
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| author | Caio Eduardo Gullo Anna Luiza Tannús Dami Amanda Pires Barbosa Aline Maria de Vita Marques Marianna Angelo Palmejani Luiz Guilherme Cernaglia Aureliano de Lima Jane Lopes Bonilha |
| author_facet | Caio Eduardo Gullo Anna Luiza Tannús Dami Amanda Pires Barbosa Aline Maria de Vita Marques Marianna Angelo Palmejani Luiz Guilherme Cernaglia Aureliano de Lima Jane Lopes Bonilha |
| author_sort | Caio Eduardo Gullo |
| collection | DOAJ |
| description | OBJECTIVE: To determine the efficacy of a quality control strategy in cervical cytology in the detection of high-grade squamous intraepithelial lesions. METHODS: Forty-two patients were selected who underwent a Pap smear and cervical uterine biopsy between April 2008 and December 2009, with evidence of a high-grade squamous intraepithelial lesion in one or both tests. The statistical parameters of the smear test were calculated before and after systematic meetings for review of the archived test results (6 years), in which the following was done: interobserver diagnostic consensus; cytohistological correlation, with the latter as gold standard; and evaluation of the therapeutic status of each patient. RESULTS: Once these controls were applied, it was noted that sensitivity and positive likelihood ratio of the test for high-grade squamous intraepithelial lesion increased 9.5% (34.5 to 44%) and 0.45% (1.64 to 2.09%), respectively, while specificity remained at 79%. Reduction in interference of false-negative results associated with errors in the analytical phase of the cytological productive process gave an estimate of failures in collection of the specimens (pre-analytical phase). CONCLUSION: In addition to improving the performance of the cytological diagnosis of the high-grade squamous intraepithelial lesion, the proposed quality control strategy allows a reflection on the causes of incorrect or conflicting scrutiny. |
| first_indexed | 2024-12-20T16:50:02Z |
| format | Article |
| id | doaj.art-bd4cd746bf454a19a0566279a77bc842 |
| institution | Directory Open Access Journal |
| issn | 2317-6385 |
| language | English |
| last_indexed | 2024-12-20T16:50:02Z |
| publishDate | 2012-03-01 |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-bd4cd746bf454a19a0566279a77bc8422022-12-21T19:32:50ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-63852012-03-011018691Results of a control quality strategy in cervical cytologyCaio Eduardo GulloAnna Luiza Tannús DamiAmanda Pires BarbosaAline Maria de Vita MarquesMarianna Angelo PalmejaniLuiz Guilherme Cernaglia Aureliano de Lima0Jane Lopes Bonilha1Faculdade de Medicina de São José do Rio PretoFaculdade de Medicina de São José do Rio PretoOBJECTIVE: To determine the efficacy of a quality control strategy in cervical cytology in the detection of high-grade squamous intraepithelial lesions. METHODS: Forty-two patients were selected who underwent a Pap smear and cervical uterine biopsy between April 2008 and December 2009, with evidence of a high-grade squamous intraepithelial lesion in one or both tests. The statistical parameters of the smear test were calculated before and after systematic meetings for review of the archived test results (6 years), in which the following was done: interobserver diagnostic consensus; cytohistological correlation, with the latter as gold standard; and evaluation of the therapeutic status of each patient. RESULTS: Once these controls were applied, it was noted that sensitivity and positive likelihood ratio of the test for high-grade squamous intraepithelial lesion increased 9.5% (34.5 to 44%) and 0.45% (1.64 to 2.09%), respectively, while specificity remained at 79%. Reduction in interference of false-negative results associated with errors in the analytical phase of the cytological productive process gave an estimate of failures in collection of the specimens (pre-analytical phase). CONCLUSION: In addition to improving the performance of the cytological diagnosis of the high-grade squamous intraepithelial lesion, the proposed quality control strategy allows a reflection on the causes of incorrect or conflicting scrutiny.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082012000100018&tlng=enEfficacyQuality controlIntraepithelial cervical neoplasiaCervix uteri |
| spellingShingle | Caio Eduardo Gullo Anna Luiza Tannús Dami Amanda Pires Barbosa Aline Maria de Vita Marques Marianna Angelo Palmejani Luiz Guilherme Cernaglia Aureliano de Lima Jane Lopes Bonilha Results of a control quality strategy in cervical cytology Einstein (São Paulo) Efficacy Quality control Intraepithelial cervical neoplasia Cervix uteri |
| title | Results of a control quality strategy in cervical cytology |
| title_full | Results of a control quality strategy in cervical cytology |
| title_fullStr | Results of a control quality strategy in cervical cytology |
| title_full_unstemmed | Results of a control quality strategy in cervical cytology |
| title_short | Results of a control quality strategy in cervical cytology |
| title_sort | results of a control quality strategy in cervical cytology |
| topic | Efficacy Quality control Intraepithelial cervical neoplasia Cervix uteri |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082012000100018&tlng=en |
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