CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION
Objective: To assess the frequency of preoperative leukocytosis and its association with wound infection. Study Design: Prospective-cross sectional, analytical study. Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Army Medical College Rawalpindi
2020-10-01
|
| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/5581/2982 |
| _version_ | 1818925079938990080 |
|---|---|
| author | Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram |
| author_facet | Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram |
| author_sort | Sadia Zainab |
| collection | DOAJ |
| description | Objective: To assess the frequency of preoperative leukocytosis and its association with wound infection.
Study Design: Prospective-cross sectional, analytical study.
Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017.
Methodology: After the approval of hospital ethics committee, 340 pregnant ladies undergoing both elective and emergency cesarean section were included in our study. The outcome of our study was the frequency of preoperative leukocytosis and its association with postoperative wound infection. SPSS version 20 was used to analyze data. The qualitative data was presented as frequency and percentage. Chi-square was used to analyze significance. A p-value ≤0.05 was taken as significant.
Results: Frequency of preoperative leukocytosis was 121 (36.6%). A total of 111 (64.1%) pregnant ladies had pre-operative leukocytosis without post-operative wound infection versus 10 (66.6%) in patients with wound infection, p≤0.05, odd ratio 3.77. The sensitivity of pre-op total leukocyte count (TLC) for prediction of post-op wound infection was 66.6% (95% CI 38.3 to 88.8%) and specificity of 65.1% (59.5% to 70.34%). Most patients, 13 (86.6%), with wound infection required only debridement and intravenous antibiotics: IV linezolid and metronidazole; rest 2(13.4%) required secondary suturing for patient recovery.
Conclusion: Preoperative leukocytosis was common in parturient undergoing cesarean section incidence of wound infection was low in this study. The post-operative wound infection risk is shown to correlate with the preoperative leukocytosis. |
| first_indexed | 2024-12-20T02:35:32Z |
| format | Article |
| id | doaj.art-bd5581a5f5504403bc96710a44a5d3bf |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-20T02:35:32Z |
| publishDate | 2020-10-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-bd5581a5f5504403bc96710a44a5d3bf2022-12-21T19:56:27ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422020-10-0170514391442CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTIONSadia Zainab0Amina Akbar1Saira Mahboob2Mobeen Ikram3Combined Military Hospital Okara/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Okara/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Okara/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital Okara/National University of Medical Sciences (NUMS) PakistanObjective: To assess the frequency of preoperative leukocytosis and its association with wound infection. Study Design: Prospective-cross sectional, analytical study. Place and Duration of Study: Department of Gynecology and Obstetrics, Combined Military Hospital, Thall, from Jan to Dec 2017. Methodology: After the approval of hospital ethics committee, 340 pregnant ladies undergoing both elective and emergency cesarean section were included in our study. The outcome of our study was the frequency of preoperative leukocytosis and its association with postoperative wound infection. SPSS version 20 was used to analyze data. The qualitative data was presented as frequency and percentage. Chi-square was used to analyze significance. A p-value ≤0.05 was taken as significant. Results: Frequency of preoperative leukocytosis was 121 (36.6%). A total of 111 (64.1%) pregnant ladies had pre-operative leukocytosis without post-operative wound infection versus 10 (66.6%) in patients with wound infection, p≤0.05, odd ratio 3.77. The sensitivity of pre-op total leukocyte count (TLC) for prediction of post-op wound infection was 66.6% (95% CI 38.3 to 88.8%) and specificity of 65.1% (59.5% to 70.34%). Most patients, 13 (86.6%), with wound infection required only debridement and intravenous antibiotics: IV linezolid and metronidazole; rest 2(13.4%) required secondary suturing for patient recovery. Conclusion: Preoperative leukocytosis was common in parturient undergoing cesarean section incidence of wound infection was low in this study. The post-operative wound infection risk is shown to correlate with the preoperative leukocytosis.https://www.pafmj.org/index.php/PAFMJ/article/view/5581/2982preoperative leukocytosispostoperative wound infectionsensitivity |
| spellingShingle | Sadia Zainab Amina Akbar Saira Mahboob Mobeen Ikram CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION Pakistan Armed Forces Medical Journal preoperative leukocytosis postoperative wound infection sensitivity |
| title | CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION |
| title_full | CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION |
| title_fullStr | CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION |
| title_full_unstemmed | CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION |
| title_short | CORRELATION OF PRE-OPERATIVE LEUKOCYTOSIS WITH POST-OPERATIVE WOUND INFECTION IN CAESAREAN-SECTION |
| title_sort | correlation of pre operative leukocytosis with post operative wound infection in caesarean section |
| topic | preoperative leukocytosis postoperative wound infection sensitivity |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/5581/2982 |
| work_keys_str_mv | AT sadiazainab correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT aminaakbar correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT sairamahboob correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection AT mobeenikram correlationofpreoperativeleukocytosiswithpostoperativewoundinfectionincaesareansection |