Genomic Sub-Classification of Ovarian Clear Cell Carcinoma Revealed by Distinct Mutational Signatures

Genomic Sub-Classification of Ovarian Clear Cell Carcinoma Revealed by Distinct Mutational Signatures

Ovarian clear cell carcinoma (OCCC) is characterized by dismal prognosis, partially due to its low sensitivity to standard chemotherapy regimen. It is also well-known for presenting unique molecular features in comparison to other epithelial ovarian cancer subtypes. Here, we aim to identify potentia...

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Bibliographic Details
Main Authors: Douglas V. N. P. Oliveira, Tine H. Schnack, Tim S. Poulsen, Anne P. Christiansen, Claus K. Høgdall, Estrid V. Høgdall
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
ovarian cancer
clear cell carcinoma
patient stratification
mutational signature
NGS
genomic instability
Online Access:https://www.mdpi.com/2072-6694/13/20/5242

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