Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing
Abstract Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) have the capacity to delay viral rebound when administered to people with HIV-1 (PWH) during anti-retroviral therapy (ART) interruption. To further enhance the performance of bNAbs through their Fc effec...
Principais autores: | Steven W. de Taeye, Angela I. Schriek, Jeffrey C. Umotoy, Marloes Grobben, Judith A. Burger, Rogier W. Sanders, Gestur Vidarsson, Manfred Wuhrer, David Falck, Neeltje A. Kootstra, Marit J. van Gils |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Nature Portfolio
2024-08-01
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coleção: | Communications Biology |
Acesso em linha: | https://doi.org/10.1038/s42003-024-06659-8 |
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