H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

Abstract Background Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome‐wide gene expression analyses have identified that elevated levels of microRNAs encoded by the H19X locus are among the most significant changes in skeletal musc...

Full description

Bibliographic Details
Main Authors: Rui Liang, Xiaopeng Shen, Fan Wang, Xin Wang, Alex DesJarlais, Anam Syed, Raymond Saba, Zhi Tan, Fang Yu, Xuan Ji, Shreesti Shrestha, Yinghong Ren, Jin Yang, Yoonjung Park, Robert J. Schwartz, Benjamin Soibam, Bradley K. McConnell, M. David Stewart, Ashok Kumar, Yu Liu
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Skeletal muscle atrophy
Protein synthesis
H19X
MicroRNAs
miR‐322
miR‐424
Online Access:https://doi.org/10.1002/jcsm.12827

Internet

https://doi.org/10.1002/jcsm.12827

Similar Items