Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs
Homologous proteins can display high structural variation due to evolutionary divergence at low sequence identity. This classical inverse relationship between sequence identity and structural similarity, established many years ago, has remained true between homologous proteins of known structure ove...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-12-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13492 |