4862F, a New Inhibitor of HIV-1 Protease, from the Culture of Streptomyces I03A-04862

4862F, a New Inhibitor of HIV-1 Protease, from the Culture of Streptomyces I03A-04862

We have isolated an extraordinary pentapeptide, called 4862F, from the culture broth of Streptomyces albosporus I03A-04862 by Diaion HP-20 macroporous adsorbent resin column, ODS-A and Sephadex LH-20 chromatography, followed by preparative HPLC. This peptide shows inhibitory activity against HIV-1 p...

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Bibliographic Details
Main Authors: Peizhen Tao, Wei Jiang, Liyan Yu, Minghua Chen, Shuoke Bai, Yexiang Wu, Xiuyong Fan, Yuqin Zhang, Yongzhen Li, Tian Zhang, Biao Dong, Maoluo Gan, Xiao Liu, Shuyi Si
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
Streptomyces albosporus
structure elucidation
HIV-1 protease inhibitor
Online Access:http://www.mdpi.com/1420-3049/18/1/236

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