Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study
This study aimed to assess the ability of modern resin-based “bioactive” materials (RBMs) to induce dentine remineralisation via mineral deposition and compare the results to those obtained with calcium silicate cements (CSMs). The following materials were employed for restoration of dentine cavitie...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/14/3/274 |
| _version_ | 1797318425071058944 |
|---|---|
| author | Marta Kunert Ireneusz Piwonski Louis Hardan Rim Bourgi Salvatore Sauro Francesco Inchingolo Monika Lukomska-Szymanska |
| author_facet | Marta Kunert Ireneusz Piwonski Louis Hardan Rim Bourgi Salvatore Sauro Francesco Inchingolo Monika Lukomska-Szymanska |
| author_sort | Marta Kunert |
| collection | DOAJ |
| description | This study aimed to assess the ability of modern resin-based “bioactive” materials (RBMs) to induce dentine remineralisation via mineral deposition and compare the results to those obtained with calcium silicate cements (CSMs). The following materials were employed for restoration of dentine cavities: CSMs: ProRoot MTA (Dentsply Sirona), MTA Angelus (Angelus), Biodentine (Septodont), and TheraCal LC (Bisco); RBMs: ACTIVA BioACTIVE Base/Liner (Pulpdent), ACTIVA Presto (Pulpdent), and Predicta Bioactive Bulk (Parkell). The evaluation of the mineral deposition was performed through scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) on the material and dentine surfaces, as well as at the dentine–material interface after immersion in simulated body fluid. Additionally, the Ca/P ratios were also calculated in all the tested groups. The specimens were analysed after setting (baseline) and at 24 h, 7, 14, and 28 days. ProRoot MTA, MTA Angelus, Biodentine, and TheraCal LC showed significant surface precipitation, which filled the gap between the material and the dentine. Conversely, the three RBMs showed only a slight ability to induce mineral precipitation, although none of them was able to remineralise the dentine–material interface. In conclusion, in terms of mineral precipitation, modern “bioactive” RBMs are not as effective as CSMs in inducing dentine remineralisation; these latter represent the only option to induce a possible reparative process at the dentin–material interface. |
| first_indexed | 2024-03-08T03:52:05Z |
| format | Article |
| id | doaj.art-bd5c0b9bdc324273be2a923cf2167b36 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-08T03:52:05Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-bd5c0b9bdc324273be2a923cf2167b362024-02-09T15:19:25ZengMDPI AGNanomaterials2079-49912024-01-0114327410.3390/nano14030274Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro StudyMarta Kunert0Ireneusz Piwonski1Louis Hardan2Rim Bourgi3Salvatore Sauro4Francesco Inchingolo5Monika Lukomska-Szymanska6Department of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, PolandDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, 163 Pomorska St., 90-236 Lodz, PolandDepartment of Restorative Dentistry, School of Dentistry, Saint-Joseph University, Beirut 1107 2180, LebanonDepartment of Restorative Dentistry, School of Dentistry, Saint-Joseph University, Beirut 1107 2180, LebanonDental Biomaterials and Minimally Invasive Dentistry, Departamento de Odontología, Facultad de Ciencias de la Salud, Universidad CEU-Cardenal Herrera C/Del Pozo ss/n, Alfara del Patriarca, 46115 Valencia, SpainDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, PolandThis study aimed to assess the ability of modern resin-based “bioactive” materials (RBMs) to induce dentine remineralisation via mineral deposition and compare the results to those obtained with calcium silicate cements (CSMs). The following materials were employed for restoration of dentine cavities: CSMs: ProRoot MTA (Dentsply Sirona), MTA Angelus (Angelus), Biodentine (Septodont), and TheraCal LC (Bisco); RBMs: ACTIVA BioACTIVE Base/Liner (Pulpdent), ACTIVA Presto (Pulpdent), and Predicta Bioactive Bulk (Parkell). The evaluation of the mineral deposition was performed through scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) on the material and dentine surfaces, as well as at the dentine–material interface after immersion in simulated body fluid. Additionally, the Ca/P ratios were also calculated in all the tested groups. The specimens were analysed after setting (baseline) and at 24 h, 7, 14, and 28 days. ProRoot MTA, MTA Angelus, Biodentine, and TheraCal LC showed significant surface precipitation, which filled the gap between the material and the dentine. Conversely, the three RBMs showed only a slight ability to induce mineral precipitation, although none of them was able to remineralise the dentine–material interface. In conclusion, in terms of mineral precipitation, modern “bioactive” RBMs are not as effective as CSMs in inducing dentine remineralisation; these latter represent the only option to induce a possible reparative process at the dentin–material interface.https://www.mdpi.com/2079-4991/14/3/274bioactive dental materialscalcium silicate materialsCa/P ratioEDSpulp cappingMTA |
| spellingShingle | Marta Kunert Ireneusz Piwonski Louis Hardan Rim Bourgi Salvatore Sauro Francesco Inchingolo Monika Lukomska-Szymanska Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study Nanomaterials bioactive dental materials calcium silicate materials Ca/P ratio EDS pulp capping MTA |
| title | Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study |
| title_full | Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study |
| title_fullStr | Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study |
| title_full_unstemmed | Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study |
| title_short | Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study |
| title_sort | dentine remineralisation induced by bioactive materials through mineral deposition an in vitro study |
| topic | bioactive dental materials calcium silicate materials Ca/P ratio EDS pulp capping MTA |
| url | https://www.mdpi.com/2079-4991/14/3/274 |
| work_keys_str_mv | AT martakunert dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT ireneuszpiwonski dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT louishardan dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT rimbourgi dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT salvatoresauro dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT francescoinchingolo dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy AT monikalukomskaszymanska dentineremineralisationinducedbybioactivematerialsthroughmineraldepositionaninvitrostudy |