Adenosquamous carcinoma of the pancreas: two case reports and review of the literature
Abstract Background Among the total reported cases of pancreatic duct adenocarcinomas, around 1–2.9% are adenosquamous carcinomas of the pancreas. Due to limited data, preoperative diagnosis is a great challenge for physicians, and it is usually set post-operational, based on the pathologist report....
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-022-03610-5 |
| _version_ | 1811335027110182912 |
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| author | Daniel Paramythiotis Filippos Kyriakidis Eleni Karlafti Triantafyllos Didangelos Ilias-Marios Oikonomou Anestis Karakatsanis Christos Poulios Eleni Chamalidou Anastasios Vagionas Antonios Michalopoulos |
| author_facet | Daniel Paramythiotis Filippos Kyriakidis Eleni Karlafti Triantafyllos Didangelos Ilias-Marios Oikonomou Anestis Karakatsanis Christos Poulios Eleni Chamalidou Anastasios Vagionas Antonios Michalopoulos |
| author_sort | Daniel Paramythiotis |
| collection | DOAJ |
| description | Abstract Background Among the total reported cases of pancreatic duct adenocarcinomas, around 1–2.9% are adenosquamous carcinomas of the pancreas. Due to limited data, preoperative diagnosis is a great challenge for physicians, and it is usually set post-operational, based on the pathologist report. We operated on two cases of adenosquamous carcinoma of the pancreas, which we present alongside the operation and treatment planning. Case report A 69-year-old Caucasian female and a 63-year-old Caucasian male presented themselves with jaundice in our department. The abdomen computed tomography and magnetic resonance imaging scans revealed lesions of the pancreas. A pancreas–duodenumectomy was performed in both patients, and the post-operational histology analysis revealed adenosquamous carcinoma of the pancreas head. The patients were discharged in good condition and received further chemotherapy treatment after surgery. Conclusions Two case reports of adenosquamous carcinoma of the pancreas are described here, which both underwent surgery resection. The limited available literature on this topic substantially limits the knowledge and guidance on treatment. A summarization of the available literature is attempted, alongside a description of possible fields of future research. |
| first_indexed | 2024-04-13T17:17:50Z |
| format | Article |
| id | doaj.art-bd5ff1fcf4f0475794b16792aa21842b |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-13T17:17:50Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-bd5ff1fcf4f0475794b16792aa21842b2022-12-22T02:38:05ZengBMCJournal of Medical Case Reports1752-19472022-10-011611910.1186/s13256-022-03610-5Adenosquamous carcinoma of the pancreas: two case reports and review of the literature Daniel Paramythiotis0Filippos Kyriakidis1Eleni Karlafti2Triantafyllos Didangelos3Ilias-Marios Oikonomou4Anestis Karakatsanis5Christos Poulios6Eleni Chamalidou7Anastasios Vagionas8Antonios Michalopoulos91st Propaedeutic Surgery Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki1st Propaedeutic Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki1st Propaedeutic Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki1st Propaedeutic Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki1st Propaedeutic Surgery Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki1st Propaedeutic Surgery Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of ThessalonikiDepartment of Pathology, School of Health Sciences, Faculty of Medicine, Aristotle University of Thessaloniki1st Propaedeutic Internal Medicine Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of ThessalonikiGeneral Hospital of Kavala1st Propaedeutic Surgery Department, AHEPA University General Hospital of Thessaloniki, Aristotle University of ThessalonikiAbstract Background Among the total reported cases of pancreatic duct adenocarcinomas, around 1–2.9% are adenosquamous carcinomas of the pancreas. Due to limited data, preoperative diagnosis is a great challenge for physicians, and it is usually set post-operational, based on the pathologist report. We operated on two cases of adenosquamous carcinoma of the pancreas, which we present alongside the operation and treatment planning. Case report A 69-year-old Caucasian female and a 63-year-old Caucasian male presented themselves with jaundice in our department. The abdomen computed tomography and magnetic resonance imaging scans revealed lesions of the pancreas. A pancreas–duodenumectomy was performed in both patients, and the post-operational histology analysis revealed adenosquamous carcinoma of the pancreas head. The patients were discharged in good condition and received further chemotherapy treatment after surgery. Conclusions Two case reports of adenosquamous carcinoma of the pancreas are described here, which both underwent surgery resection. The limited available literature on this topic substantially limits the knowledge and guidance on treatment. A summarization of the available literature is attempted, alongside a description of possible fields of future research.https://doi.org/10.1186/s13256-022-03610-5AdenosquamousCarcinomaPancreasAdenocarcinomaDuodenumSurgery |
| spellingShingle | Daniel Paramythiotis Filippos Kyriakidis Eleni Karlafti Triantafyllos Didangelos Ilias-Marios Oikonomou Anestis Karakatsanis Christos Poulios Eleni Chamalidou Anastasios Vagionas Antonios Michalopoulos Adenosquamous carcinoma of the pancreas: two case reports and review of the literature Journal of Medical Case Reports Adenosquamous Carcinoma Pancreas Adenocarcinoma Duodenum Surgery |
| title | Adenosquamous carcinoma of the pancreas: two case reports and review of the literature |
| title_full | Adenosquamous carcinoma of the pancreas: two case reports and review of the literature |
| title_fullStr | Adenosquamous carcinoma of the pancreas: two case reports and review of the literature |
| title_full_unstemmed | Adenosquamous carcinoma of the pancreas: two case reports and review of the literature |
| title_short | Adenosquamous carcinoma of the pancreas: two case reports and review of the literature |
| title_sort | adenosquamous carcinoma of the pancreas two case reports and review of the literature |
| topic | Adenosquamous Carcinoma Pancreas Adenocarcinoma Duodenum Surgery |
| url | https://doi.org/10.1186/s13256-022-03610-5 |
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