Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
Introduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called &...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-03-01
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Series: | Frontiers in Pharmacology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/full |
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author | Isabelle eArnet Philipp N Walter Kurt E Hersberger |
author_facet | Isabelle eArnet Philipp N Walter Kurt E Hersberger |
author_sort | Isabelle eArnet |
collection | DOAJ |
description | Introduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called "electronic medication event monitoring" but is currently limited to the monitoring of a single drug therapy. Aim: Introducing a new technology; a clear, self-adhesive polymer film, with printed loops of conductive wires that can be affixed to multidrug punch cards for the electronic adherence monitoring of multiple medication regimens (POEMS); illustrating potential benefits for patient care. We present a preliminary report with one patient experience. Materials and methods: Our illustrative case was supplied with a prefilled 7-day multiple medication punch card with unit-of-use doses for specific times of the day (6 pills in the morning cavity, 2 pills in the evening cavity and 1 pill in case of insomnia in the bedtime cavity), with the new electronic film affixed on it. Results: The intake times over 1 week were extremely skewed (median intake hours at 2:00 pm for the morning doses and at 6:40 pm for the evening doses). After an intervention aimed at optimising the timing adherence, the morning and evening intake hours became more balanced, with 42.3% of correct dosing intervals (± 3h) for drugs with twice daily intake (vs. 0% before the intervention). Discussion: The electronic monitoring of the entire therapy revealed an intake pattern that would have remained undiscovered with any other device and allowed a personalized intervention to correct an inadequate medication intake behavior. POEMS may guide health professionals when they need to optimise a pharmacotherapy because of suspected insufficient adherence. Further, knowing the intake pattern of the entire pharmacotherapy can elucidate unreached clinical outcome, drug-drug interactions, and drug resistance. In the |
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format | Article |
id | doaj.art-bd6054631af34cc193aea24aef630754 |
institution | Directory Open Access Journal |
issn | 1663-9812 |
language | English |
last_indexed | 2024-12-20T12:20:15Z |
publishDate | 2013-03-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Pharmacology |
spelling | doaj.art-bd6054631af34cc193aea24aef6307542022-12-21T19:41:00ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122013-03-01410.3389/fphar.2013.0002640266Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherenceIsabelle eArnet0Philipp N Walter1Kurt E Hersberger2Pharmaceutical Care Research Group, University of BaselPharmaceutical Care Research Group, University of BaselPharmaceutical Care Research Group, University of BaselIntroduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called "electronic medication event monitoring" but is currently limited to the monitoring of a single drug therapy. Aim: Introducing a new technology; a clear, self-adhesive polymer film, with printed loops of conductive wires that can be affixed to multidrug punch cards for the electronic adherence monitoring of multiple medication regimens (POEMS); illustrating potential benefits for patient care. We present a preliminary report with one patient experience. Materials and methods: Our illustrative case was supplied with a prefilled 7-day multiple medication punch card with unit-of-use doses for specific times of the day (6 pills in the morning cavity, 2 pills in the evening cavity and 1 pill in case of insomnia in the bedtime cavity), with the new electronic film affixed on it. Results: The intake times over 1 week were extremely skewed (median intake hours at 2:00 pm for the morning doses and at 6:40 pm for the evening doses). After an intervention aimed at optimising the timing adherence, the morning and evening intake hours became more balanced, with 42.3% of correct dosing intervals (± 3h) for drugs with twice daily intake (vs. 0% before the intervention). Discussion: The electronic monitoring of the entire therapy revealed an intake pattern that would have remained undiscovered with any other device and allowed a personalized intervention to correct an inadequate medication intake behavior. POEMS may guide health professionals when they need to optimise a pharmacotherapy because of suspected insufficient adherence. Further, knowing the intake pattern of the entire pharmacotherapy can elucidate unreached clinical outcome, drug-drug interactions, and drug resistance. In thehttp://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/fullCommunity Pharmacy Servicesadherenceelectronic monitoringmultidrug punch cardprinted electronics |
spellingShingle | Isabelle eArnet Philipp N Walter Kurt E Hersberger Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence Frontiers in Pharmacology Community Pharmacy Services adherence electronic monitoring multidrug punch card printed electronics |
title | Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence |
title_full | Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence |
title_fullStr | Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence |
title_full_unstemmed | Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence |
title_short | Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence |
title_sort | polymedication electronic monitoring system poems a new technology for measuring adherence |
topic | Community Pharmacy Services adherence electronic monitoring multidrug punch card printed electronics |
url | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/full |
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