Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence

Introduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called &...

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Main Authors: Isabelle eArnet, Philipp N Walter, Kurt E Hersberger
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/full
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author Isabelle eArnet
Philipp N Walter
Kurt E Hersberger
author_facet Isabelle eArnet
Philipp N Walter
Kurt E Hersberger
author_sort Isabelle eArnet
collection DOAJ
description Introduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called "electronic medication event monitoring" but is currently limited to the monitoring of a single drug therapy. Aim: Introducing a new technology; a clear, self-adhesive polymer film, with printed loops of conductive wires that can be affixed to multidrug punch cards for the electronic adherence monitoring of multiple medication regimens (POEMS); illustrating potential benefits for patient care. We present a preliminary report with one patient experience. Materials and methods: Our illustrative case was supplied with a prefilled 7-day multiple medication punch card with unit-of-use doses for specific times of the day (6 pills in the morning cavity, 2 pills in the evening cavity and 1 pill in case of insomnia in the bedtime cavity), with the new electronic film affixed on it. Results: The intake times over 1 week were extremely skewed (median intake hours at 2:00 pm for the morning doses and at 6:40 pm for the evening doses). After an intervention aimed at optimising the timing adherence, the morning and evening intake hours became more balanced, with 42.3% of correct dosing intervals (± 3h) for drugs with twice daily intake (vs. 0% before the intervention). Discussion: The electronic monitoring of the entire therapy revealed an intake pattern that would have remained undiscovered with any other device and allowed a personalized intervention to correct an inadequate medication intake behavior. POEMS may guide health professionals when they need to optimise a pharmacotherapy because of suspected insufficient adherence. Further, knowing the intake pattern of the entire pharmacotherapy can elucidate unreached clinical outcome, drug-drug interactions, and drug resistance. In the
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spelling doaj.art-bd6054631af34cc193aea24aef6307542022-12-21T19:41:00ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122013-03-01410.3389/fphar.2013.0002640266Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherenceIsabelle eArnet0Philipp N Walter1Kurt E Hersberger2Pharmaceutical Care Research Group, University of BaselPharmaceutical Care Research Group, University of BaselPharmaceutical Care Research Group, University of BaselIntroduction: Reliable and precise measurement of patient adherence to medications is feasible by incorporating a microcircuitry into pharmaceutical packages of various designs, such that the manoeuvres needed to remove a dose of drug are detected, time-stamped, and stored. The principle is called "electronic medication event monitoring" but is currently limited to the monitoring of a single drug therapy. Aim: Introducing a new technology; a clear, self-adhesive polymer film, with printed loops of conductive wires that can be affixed to multidrug punch cards for the electronic adherence monitoring of multiple medication regimens (POEMS); illustrating potential benefits for patient care. We present a preliminary report with one patient experience. Materials and methods: Our illustrative case was supplied with a prefilled 7-day multiple medication punch card with unit-of-use doses for specific times of the day (6 pills in the morning cavity, 2 pills in the evening cavity and 1 pill in case of insomnia in the bedtime cavity), with the new electronic film affixed on it. Results: The intake times over 1 week were extremely skewed (median intake hours at 2:00 pm for the morning doses and at 6:40 pm for the evening doses). After an intervention aimed at optimising the timing adherence, the morning and evening intake hours became more balanced, with 42.3% of correct dosing intervals (± 3h) for drugs with twice daily intake (vs. 0% before the intervention). Discussion: The electronic monitoring of the entire therapy revealed an intake pattern that would have remained undiscovered with any other device and allowed a personalized intervention to correct an inadequate medication intake behavior. POEMS may guide health professionals when they need to optimise a pharmacotherapy because of suspected insufficient adherence. Further, knowing the intake pattern of the entire pharmacotherapy can elucidate unreached clinical outcome, drug-drug interactions, and drug resistance. In thehttp://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/fullCommunity Pharmacy Servicesadherenceelectronic monitoringmultidrug punch cardprinted electronics
spellingShingle Isabelle eArnet
Philipp N Walter
Kurt E Hersberger
Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
Frontiers in Pharmacology
Community Pharmacy Services
adherence
electronic monitoring
multidrug punch card
printed electronics
title Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
title_full Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
title_fullStr Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
title_full_unstemmed Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
title_short Polymedication Electronic Monitoring System (POEMS) – a new technology for measuring adherence
title_sort polymedication electronic monitoring system poems a new technology for measuring adherence
topic Community Pharmacy Services
adherence
electronic monitoring
multidrug punch card
printed electronics
url http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00026/full
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