Mild hypoxia enhances proliferation and multipotency of human neural stem cells.

Neural stem cells (NSCs) represent an optimal tool for studies and therapy of neurodegenerative diseases. We recently established a v-myc immortalized human NSC (IhNSC) line, which retains stem properties comparable to parental cells. Oxygen concentration is one of the most crucial environmental con...

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Bibliographic Details
Main Authors: Guido Santilli, Giuseppe Lamorte, Luigi Carlessi, Daniela Ferrari, Laura Rota Nodari, Elena Binda, Domenico Delia, Angelo L Vescovi, Lidia De Filippis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2797394?pdf=render