P3 mAb: an immunogenic anti-NeuGcGM3 antibody with unusual immunoregulatory properties.

P3 is a murine IgM mAb that recognize N-glycolilated gangliosides, sulphatides and antigens expressed in melanoma, breast and lung human tumors. This antibody has the ability to trigger an IgG antibody response in the syngeneic BALB/c model, even when it is administered in the absence of adjuvant or...

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Bibliographic Details
Main Authors: Darel eMartínez, Nely eRodríguez, Tania eGriñán, Teresa eRondón, Ana María Vázquez, Rolando ePérez, Ana María eHernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00094/full