Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases
Oxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a key contributor to the development of various common diseases. Counteracting these oxidants is considered an effective strategy to mitigate the levels of oxidative stress in organisms. Numerous studies have in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/25/6/3264 |
| _version_ | 1797240707739549696 |
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| author | Adele Muscolo Oliva Mariateresa Torello Giulio Russo Mariateresa |
| author_facet | Adele Muscolo Oliva Mariateresa Torello Giulio Russo Mariateresa |
| author_sort | Adele Muscolo |
| collection | DOAJ |
| description | Oxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a key contributor to the development of various common diseases. Counteracting these oxidants is considered an effective strategy to mitigate the levels of oxidative stress in organisms. Numerous studies have indicated an inverse correlation between the consumption of vegetables and fruits and the risk of chronic diseases, attributing these health benefits to the presence of antioxidant phytochemicals in these foods. Phytochemicals, present in a wide range of foods and medicinal plants, play a pivotal role in preventing and treating chronic diseases induced by oxidative stress by working as antioxidants. These compounds exhibit potent antioxidant, anti-inflammatory, anti-aging, anticancer, and protective properties against cardiovascular diseases, diabetes mellitus, obesity, and neurodegenerative conditions. This comprehensive review delves into the significance of these compounds in averting and managing chronic diseases, elucidating the key sources of these invaluable elements. Additionally, it provides a summary of recent advancements in understanding the health benefits associated with antioxidant phytochemicals. |
| first_indexed | 2024-04-24T18:11:43Z |
| format | Article |
| id | doaj.art-bd65fed8b01a4349ad1f58c75f799156 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-04-24T18:11:43Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-bd65fed8b01a4349ad1f58c75f7991562024-03-27T13:45:32ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672024-03-01256326410.3390/ijms25063264Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of DiseasesAdele Muscolo0Oliva Mariateresa1Torello Giulio2Russo Mariateresa3Department of AGRARIA, “Mediterranea” University, Feo di Vito, 89124 Reggio Calabria, ItalyDepartment of AGRARIA, “Mediterranea” University, Feo di Vito, 89124 Reggio Calabria, ItalyTL Pharma Via Lago di Martignano, 18, 65129 Pescara, ItalyDepartment of AGRARIA, “Mediterranea” University, Feo di Vito, 89124 Reggio Calabria, ItalyOxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a key contributor to the development of various common diseases. Counteracting these oxidants is considered an effective strategy to mitigate the levels of oxidative stress in organisms. Numerous studies have indicated an inverse correlation between the consumption of vegetables and fruits and the risk of chronic diseases, attributing these health benefits to the presence of antioxidant phytochemicals in these foods. Phytochemicals, present in a wide range of foods and medicinal plants, play a pivotal role in preventing and treating chronic diseases induced by oxidative stress by working as antioxidants. These compounds exhibit potent antioxidant, anti-inflammatory, anti-aging, anticancer, and protective properties against cardiovascular diseases, diabetes mellitus, obesity, and neurodegenerative conditions. This comprehensive review delves into the significance of these compounds in averting and managing chronic diseases, elucidating the key sources of these invaluable elements. Additionally, it provides a summary of recent advancements in understanding the health benefits associated with antioxidant phytochemicals.https://www.mdpi.com/1422-0067/25/6/3264antioxidant phytochemicalsfree radicalschronic diseasehealth benefitspolyphenols |
| spellingShingle | Adele Muscolo Oliva Mariateresa Torello Giulio Russo Mariateresa Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases International Journal of Molecular Sciences antioxidant phytochemicals free radicals chronic disease health benefits polyphenols |
| title | Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases |
| title_full | Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases |
| title_fullStr | Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases |
| title_full_unstemmed | Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases |
| title_short | Oxidative Stress: The Role of Antioxidant Phytochemicals in the Prevention and Treatment of Diseases |
| title_sort | oxidative stress the role of antioxidant phytochemicals in the prevention and treatment of diseases |
| topic | antioxidant phytochemicals free radicals chronic disease health benefits polyphenols |
| url | https://www.mdpi.com/1422-0067/25/6/3264 |
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