Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action
We examined risk associated with antibiotics used for Clostridioides difficile infection (CDI) at a single site from 2018 through 2020. Overall, 78 patients had nonrecurrent infections. Among inpatient antibiotics, intravenous meropenem had the highest CDI rate (3.56 per 1,000 days of therapy; n = 2...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X22002868/type/journal_article |
| _version_ | 1811157184388530176 |
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| author | Andrew T. Dysangco Tamra M. Pierce Dawn M. Bravata |
| author_facet | Andrew T. Dysangco Tamra M. Pierce Dawn M. Bravata |
| author_sort | Andrew T. Dysangco |
| collection | DOAJ |
| description | We examined risk associated with antibiotics used for Clostridioides difficile infection (CDI) at a single site from 2018 through 2020. Overall, 78 patients had nonrecurrent infections. Among inpatient antibiotics, intravenous meropenem had the highest CDI rate (3.56 per 1,000 days of therapy; n = 2 cases). Among outpatient antibiotics, metronidazole had the highest rate (0.071 per 1,000 pills dispensed; n = 3 cases). |
| first_indexed | 2024-04-10T05:02:51Z |
| format | Article |
| id | doaj.art-bd66b8a6696a47a9b6db63f6d0df4c9f |
| institution | Directory Open Access Journal |
| issn | 2732-494X |
| language | English |
| last_indexed | 2024-04-10T05:02:51Z |
| publishDate | 2022-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj.art-bd66b8a6696a47a9b6db63f6d0df4c9f2023-03-09T12:28:16ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2022-01-01210.1017/ash.2022.286Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in actionAndrew T. Dysangco0https://orcid.org/0000-0002-2873-5776Tamra M. Pierce1Dawn M. Bravata2https://orcid.org/0000-0002-3048-2536Department of Veterans’ Affairs (VA) Health Services Research and Development (HSR&D) Precision Monitoring to Transform Care (PRISM) Quality Enhancement Research Initiative (QUERI), Indianapolis, Indiana VA HSR&D Center for Health Information and Communication (CHIC), Richard L. Roudebush VA Medical Center, Indianapolis, Indiana Medicine Service, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana Department of Medicine, Indiana University School of Medicine, Indianapolis, IndianaPharmacy Service, Richard L. Roudebush VA Medical Center, Indianapolis, IndianaDepartment of Veterans’ Affairs (VA) Health Services Research and Development (HSR&D) Precision Monitoring to Transform Care (PRISM) Quality Enhancement Research Initiative (QUERI), Indianapolis, Indiana VA HSR&D Center for Health Information and Communication (CHIC), Richard L. Roudebush VA Medical Center, Indianapolis, Indiana Medicine Service, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana Regenstrief Institute, Indianapolis, IndianaWe examined risk associated with antibiotics used for Clostridioides difficile infection (CDI) at a single site from 2018 through 2020. Overall, 78 patients had nonrecurrent infections. Among inpatient antibiotics, intravenous meropenem had the highest CDI rate (3.56 per 1,000 days of therapy; n = 2 cases). Among outpatient antibiotics, metronidazole had the highest rate (0.071 per 1,000 pills dispensed; n = 3 cases).https://www.cambridge.org/core/product/identifier/S2732494X22002868/type/journal_article |
| spellingShingle | Andrew T. Dysangco Tamra M. Pierce Dawn M. Bravata Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action |
| title_full | Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action |
| title_fullStr | Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action |
| title_full_unstemmed | Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action |
| title_short | Risk of antibiotics associated with Clostridioides difficile infection: Antibiotic stewardship in action |
| title_sort | risk of antibiotics associated with clostridioides difficile infection antibiotic stewardship in action |
| url | https://www.cambridge.org/core/product/identifier/S2732494X22002868/type/journal_article |
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