Post-infectious neurological disorders
A multitude of environmental factors can result in breakdown of immune tolerance in susceptible hosts. Infectious pathogens are among the most important environmental triggers in the pathogenesis of autoimmunity. Certain autoimmune disorders have a strong association with specific infections. Severa...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-08-01
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| Series: | Therapeutic Advances in Neurological Disorders |
| Online Access: | https://doi.org/10.1177/1756286420952901 |
| _version_ | 1811311811998253056 |
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| author | Kyle M. Blackburn Cynthia Wang |
| author_facet | Kyle M. Blackburn Cynthia Wang |
| author_sort | Kyle M. Blackburn |
| collection | DOAJ |
| description | A multitude of environmental factors can result in breakdown of immune tolerance in susceptible hosts. Infectious pathogens are among the most important environmental triggers in the pathogenesis of autoimmunity. Certain autoimmune disorders have a strong association with specific infections. Several neurological autoimmune disorders are thought to occur through post-infectious mechanisms. In this review, we discuss the proposed mechanisms underlying pathogen-induced autoimmunity, and highlight the clinical presentation and treatment of several post-infectious autoimmune neurological disorders. We also highlight post-infectious neurological disorders in the setting of recent outbreaks. |
| first_indexed | 2024-04-13T10:25:34Z |
| format | Article |
| id | doaj.art-bd6f6b6ebf924c7fb3cc2bb782be88f2 |
| institution | Directory Open Access Journal |
| issn | 1756-2864 |
| language | English |
| last_indexed | 2024-04-13T10:25:34Z |
| publishDate | 2020-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Neurological Disorders |
| spelling | doaj.art-bd6f6b6ebf924c7fb3cc2bb782be88f22022-12-22T02:50:21ZengSAGE PublishingTherapeutic Advances in Neurological Disorders1756-28642020-08-011310.1177/1756286420952901Post-infectious neurological disordersKyle M. BlackburnCynthia WangA multitude of environmental factors can result in breakdown of immune tolerance in susceptible hosts. Infectious pathogens are among the most important environmental triggers in the pathogenesis of autoimmunity. Certain autoimmune disorders have a strong association with specific infections. Several neurological autoimmune disorders are thought to occur through post-infectious mechanisms. In this review, we discuss the proposed mechanisms underlying pathogen-induced autoimmunity, and highlight the clinical presentation and treatment of several post-infectious autoimmune neurological disorders. We also highlight post-infectious neurological disorders in the setting of recent outbreaks.https://doi.org/10.1177/1756286420952901 |
| spellingShingle | Kyle M. Blackburn Cynthia Wang Post-infectious neurological disorders Therapeutic Advances in Neurological Disorders |
| title | Post-infectious neurological disorders |
| title_full | Post-infectious neurological disorders |
| title_fullStr | Post-infectious neurological disorders |
| title_full_unstemmed | Post-infectious neurological disorders |
| title_short | Post-infectious neurological disorders |
| title_sort | post infectious neurological disorders |
| url | https://doi.org/10.1177/1756286420952901 |
| work_keys_str_mv | AT kylemblackburn postinfectiousneurologicaldisorders AT cynthiawang postinfectiousneurologicaldisorders |