Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
TEAD (TEA/ATTS domain) transcription factors are the most distal effectors of the Hippo pathway. YAP (Yes-associated protein) is a coactivator protein which, upon binding to TEAD proteins, stimulates their transcriptional activity. Since the Hippo pathway is deregulated in various cancers, designing...
| Автори: | , , , , , , , , , |
|---|---|
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
eLife Sciences Publications Ltd
2017-04-01
|
| Серія: | eLife |
| Предмети: | |
| Онлайн доступ: | https://elifesciences.org/articles/25068 |