Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review
Cardiac involvement by COVID-19 in children occurs most often as a part of the multisystem infl ammatory syndrome by children (MIS-C) and rarely as an isolated fi nding; affected children are predominantly older males. We present retrospective analysis data of 10 children...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Bulgarian |
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Pensoft Publishers
2022-04-01
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| Series: | Българска кардиология |
| Subjects: | |
| Online Access: | https://journal.bgcardio.org/article/80076/download/pdf/ |
| _version_ | 1797426567330136064 |
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| author | Zornitsa Vassileva Anna Kaneva Anna Dasheva Kameliya Genova |
| author_facet | Zornitsa Vassileva Anna Kaneva Anna Dasheva Kameliya Genova |
| author_sort | Zornitsa Vassileva |
| collection | DOAJ |
| description | Cardiac involvement by COVID-19 in children occurs most often as a part of the multisystem infl ammatory syndrome by children (MIS-C) and rarely as an isolated fi nding; affected children are predominantly older males. We present retrospective analysis data of 10 children with myocardial involvement within COVID-19, who were admitted at the Pediatric Cardiology Department of the National Heart Hospital – Sofi a. The main clinical symptoms were fever, heart failure, and gastrointestinal complaints, and the typical laboratory constellation included pronounced leukocytosis with extreme granulocytosis, signifi cant elevation of infl ammatory markers, increased serum troponin levels, and serologic evidence of contact with SARS-CoV2. Chest X-ray showed cardiomegaly and pulmonary hypervolemia; ECG changes were diverse and included abnormal repolarization and rhythm and conduction disturbances. Echocardiography revealed left ventricular dilation with depressed contractility, and cardiac MRI demonstrated myocardial edema and necrosis. Following immunomodulatory treatment, rapid recovery was observed. However, in most cases, the MRI changes persisted 6 months after the onset of symptoms, which makes the long-term prognosis unclear. We have reviewed our results considering the recent publications in the international databases regarding cardiac involvement by COVID-19 in children. |
| first_indexed | 2024-03-09T08:32:04Z |
| format | Article |
| id | doaj.art-bd75ee9dc28e4c58b65ad4bc341b3730 |
| institution | Directory Open Access Journal |
| issn | 2683-1015 |
| language | Bulgarian |
| last_indexed | 2024-03-09T08:32:04Z |
| publishDate | 2022-04-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Българска кардиология |
| spelling | doaj.art-bd75ee9dc28e4c58b65ad4bc341b37302023-12-02T19:37:43ZbulPensoft PublishersБългарска кардиология2683-10152022-04-01281638310.3897/bgcardio.28.e8007680076Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature reviewZornitsa Vassileva0Anna Kaneva1Anna Dasheva2Kameliya Genova3National Cardiology HosptialNational Cardiology HospitalSpecialized Children’s Hospital “Prof. Ivan Mitev”University Hospital “N. I. Pirogov”Cardiac involvement by COVID-19 in children occurs most often as a part of the multisystem infl ammatory syndrome by children (MIS-C) and rarely as an isolated fi nding; affected children are predominantly older males. We present retrospective analysis data of 10 children with myocardial involvement within COVID-19, who were admitted at the Pediatric Cardiology Department of the National Heart Hospital – Sofi a. The main clinical symptoms were fever, heart failure, and gastrointestinal complaints, and the typical laboratory constellation included pronounced leukocytosis with extreme granulocytosis, signifi cant elevation of infl ammatory markers, increased serum troponin levels, and serologic evidence of contact with SARS-CoV2. Chest X-ray showed cardiomegaly and pulmonary hypervolemia; ECG changes were diverse and included abnormal repolarization and rhythm and conduction disturbances. Echocardiography revealed left ventricular dilation with depressed contractility, and cardiac MRI demonstrated myocardial edema and necrosis. Following immunomodulatory treatment, rapid recovery was observed. However, in most cases, the MRI changes persisted 6 months after the onset of symptoms, which makes the long-term prognosis unclear. We have reviewed our results considering the recent publications in the international databases regarding cardiac involvement by COVID-19 in children.https://journal.bgcardio.org/article/80076/download/pdf/cardiac involvementchildrenCOVID-19SARS-CoV2 |
| spellingShingle | Zornitsa Vassileva Anna Kaneva Anna Dasheva Kameliya Genova Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review Българска кардиология cardiac involvement children COVID-19 SARS-CoV2 |
| title | Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review |
| title_full | Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review |
| title_fullStr | Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review |
| title_full_unstemmed | Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review |
| title_short | Cardiаc involvement by COVID-19 in children: retrospective analysis of 10 cases and literature review |
| title_sort | cardiаc involvement by covid 19 in children retrospective analysis of 10 cases and literature review |
| topic | cardiac involvement children COVID-19 SARS-CoV2 |
| url | https://journal.bgcardio.org/article/80076/download/pdf/ |
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