Hijacking and Use of Host Kinases by Chlamydiae
<i>Chlamydia</i> species are causative agents of sexually transmitted infections, blinding trachoma, and animal infections with zoonotic potential. Being an obligate intracellular pathogen, <i>Chlamydia</i> relies on the host cell for its survival and development, subverting...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/9/12/1034 |
| _version_ | 1797545198775959552 |
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| author | Prakash Sah Erika I. Lutter |
| author_facet | Prakash Sah Erika I. Lutter |
| author_sort | Prakash Sah |
| collection | DOAJ |
| description | <i>Chlamydia</i> species are causative agents of sexually transmitted infections, blinding trachoma, and animal infections with zoonotic potential. Being an obligate intracellular pathogen, <i>Chlamydia</i> relies on the host cell for its survival and development, subverting various host cell processes throughout the infection cycle. A key subset of host proteins utilized by <i>Chlamydia</i> include an assortment of host kinase signaling networks which are vital for many chlamydial processes including entry, nutrient acquisition, and suppression of host cell apoptosis. In this review, we summarize the recent advancements in our understanding of host kinase subversion by <i>Chlamydia</i>. |
| first_indexed | 2024-03-10T14:12:03Z |
| format | Article |
| id | doaj.art-bd794083ae81444daa5044bcef2fc0d9 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T14:12:03Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-bd794083ae81444daa5044bcef2fc0d92023-11-21T00:07:19ZengMDPI AGPathogens2076-08172020-12-01912103410.3390/pathogens9121034Hijacking and Use of Host Kinases by ChlamydiaePrakash Sah0Erika I. Lutter1Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK 74078, USADepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK 74078, USA<i>Chlamydia</i> species are causative agents of sexually transmitted infections, blinding trachoma, and animal infections with zoonotic potential. Being an obligate intracellular pathogen, <i>Chlamydia</i> relies on the host cell for its survival and development, subverting various host cell processes throughout the infection cycle. A key subset of host proteins utilized by <i>Chlamydia</i> include an assortment of host kinase signaling networks which are vital for many chlamydial processes including entry, nutrient acquisition, and suppression of host cell apoptosis. In this review, we summarize the recent advancements in our understanding of host kinase subversion by <i>Chlamydia</i>.https://www.mdpi.com/2076-0817/9/12/1034<i>Chlamydia</i>kinaseinfectionphosphorylationsignaling |
| spellingShingle | Prakash Sah Erika I. Lutter Hijacking and Use of Host Kinases by Chlamydiae Pathogens <i>Chlamydia</i> kinase infection phosphorylation signaling |
| title | Hijacking and Use of Host Kinases by Chlamydiae |
| title_full | Hijacking and Use of Host Kinases by Chlamydiae |
| title_fullStr | Hijacking and Use of Host Kinases by Chlamydiae |
| title_full_unstemmed | Hijacking and Use of Host Kinases by Chlamydiae |
| title_short | Hijacking and Use of Host Kinases by Chlamydiae |
| title_sort | hijacking and use of host kinases by chlamydiae |
| topic | <i>Chlamydia</i> kinase infection phosphorylation signaling |
| url | https://www.mdpi.com/2076-0817/9/12/1034 |
| work_keys_str_mv | AT prakashsah hijackinganduseofhostkinasesbychlamydiae AT erikailutter hijackinganduseofhostkinasesbychlamydiae |