Elevated levels of neutrophil related chemokine citrullinated histone H3, interleukin-8 and C-reaction protein in patients with immune checkpoint inhibitor therapy: predictive biomarkers for response to treatment

Elevated levels of neutrophil related chemokine citrullinated histone H3, interleukin-8 and C-reaction protein in patients with immune checkpoint inhibitor therapy: predictive biomarkers for response to treatment

Abstract Background Immune checkpoint inhibitor (ICI) therapy has been used in various tumors. The biomarkers predictive of a response to ICI treatment remain unclear, and additional and combined biomarkers are urgently needed. Secreted factors related to the tumor microenvironment (TME) have been e...

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Bibliographic Details
Main Authors: Xueping Wang, Hao Huang, Lin Zhang, Yaxian Wu, Yingsheng Wen, Xuezi Weng, Qi Chen, Wanli Liu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cancer Cell International
Subjects:
Cancer
H3Cit
Neutrophil extracellular traps
Immune checkpoint inhibitors
Serum biomarker
Online Access:https://doi.org/10.1186/s12935-023-02994-8

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