Brittle teeth with brittle bone in a family for four generations: Case report and literature review
Dentinogenesis imperfect (DI) is a hereditary dentine disorder affecting both deciduous and permanent teeth. DI is caused by mutations in genes encoding for type I collagen leading to discoloration of teeth. Shield around 30 years ago classified DI into 3 types (type I, II, and III). DI type I is as...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Contemporary Clinical Dentistry |
| Subjects: | |
| Online Access: | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=2;spage=197;epage=201;aulast=Shilpa |
| _version_ | 1818140942975107072 |
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| author | P S Shilpa Chaya M David Rachna Kaul C J Sanjay B K Ram Narayan |
| author_facet | P S Shilpa Chaya M David Rachna Kaul C J Sanjay B K Ram Narayan |
| author_sort | P S Shilpa |
| collection | DOAJ |
| description | Dentinogenesis imperfect (DI) is a hereditary dentine disorder affecting both deciduous and permanent teeth. DI is caused by mutations in genes encoding for type I collagen leading to discoloration of teeth. Shield around 30 years ago classified DI into 3 types (type I, II, and III). DI type I is associated with osteogenesis imperfect (OI), which is an inheritable disorder of connective tissue. Bone fragility and fracture of bone with minor trauma are hallmarks of this disorder. The objective of this article is to report and review a rare case of DI with OI affecting 4 generations of the family. Through this article, we intend to highlight genetic influence that affected a family for many generations, discuss the oral manifestations that can lead to the diagnosis of OI, and the importance of early diagnosis of OI. |
| first_indexed | 2024-12-11T10:52:00Z |
| format | Article |
| id | doaj.art-bd7d1b7ff36846a88dc60d3b026a64fd |
| institution | Directory Open Access Journal |
| issn | 0976-237X 0976-2361 |
| language | English |
| last_indexed | 2024-12-11T10:52:00Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Contemporary Clinical Dentistry |
| spelling | doaj.art-bd7d1b7ff36846a88dc60d3b026a64fd2022-12-22T01:10:16ZengWolters Kluwer Medknow PublicationsContemporary Clinical Dentistry0976-237X0976-23612012-01-013219720110.4103/0976-237X.96822Brittle teeth with brittle bone in a family for four generations: Case report and literature reviewP S ShilpaChaya M DavidRachna KaulC J SanjayB K Ram NarayanDentinogenesis imperfect (DI) is a hereditary dentine disorder affecting both deciduous and permanent teeth. DI is caused by mutations in genes encoding for type I collagen leading to discoloration of teeth. Shield around 30 years ago classified DI into 3 types (type I, II, and III). DI type I is associated with osteogenesis imperfect (OI), which is an inheritable disorder of connective tissue. Bone fragility and fracture of bone with minor trauma are hallmarks of this disorder. The objective of this article is to report and review a rare case of DI with OI affecting 4 generations of the family. Through this article, we intend to highlight genetic influence that affected a family for many generations, discuss the oral manifestations that can lead to the diagnosis of OI, and the importance of early diagnosis of OI.http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=2;spage=197;epage=201;aulast=ShilpaDentinogenesis imperfectaopalescent teethosteogenesis imperfecta |
| spellingShingle | P S Shilpa Chaya M David Rachna Kaul C J Sanjay B K Ram Narayan Brittle teeth with brittle bone in a family for four generations: Case report and literature review Contemporary Clinical Dentistry Dentinogenesis imperfecta opalescent teeth osteogenesis imperfecta |
| title | Brittle teeth with brittle bone in a family for four generations: Case report and literature review |
| title_full | Brittle teeth with brittle bone in a family for four generations: Case report and literature review |
| title_fullStr | Brittle teeth with brittle bone in a family for four generations: Case report and literature review |
| title_full_unstemmed | Brittle teeth with brittle bone in a family for four generations: Case report and literature review |
| title_short | Brittle teeth with brittle bone in a family for four generations: Case report and literature review |
| title_sort | brittle teeth with brittle bone in a family for four generations case report and literature review |
| topic | Dentinogenesis imperfecta opalescent teeth osteogenesis imperfecta |
| url | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2012;volume=3;issue=2;spage=197;epage=201;aulast=Shilpa |
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