Clinical evaluation of a matrix metalloproteinase-12 cleaved fragment of titin as a cardiovascular serological biomarker

Clinical evaluation of a matrix metalloproteinase-12 cleaved fragment of titin as a cardiovascular serological biomarker

<p>Abstract</p> <p>Background</p> <p>Titin is a muscle-specific protein found in cardiac and skeletal muscles which is responsible for restoring passive tension. Levels and functioning of titin have been shown to be affected by cardiac damage. Due to the inherent diffic...

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Bibliographic Details
Main Authors: Vassiliadis Efstathios, Rasmussen Lars M, Byrjalsen Inger, Larsen Dorthe, Chaturvedi Rajiv, Hosbond Susanne, Saabye Lotte, Diederichsen Axel CP, Genovese Federica, Duffin Kevin L, Zheng Qinlong, Chen Xiaoliang, Leeming Diana J, Christiansen Claus, Karsdal Morten A
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Translational Medicine
Subjects:
Titin
CVD
MMP-12
Cardiovascular
Acute myocardial infarction
Biomarker
Neoepitope
Online Access:http://www.translational-medicine.com/content/10/1/140

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