Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence
Purpose/Context. This article seeks to understand the meaning that the possibility of making genetic changes in human beings before birth would have for a group of individuals residing in Bogotá. The study focuses on the application of the CRISPR-Cas9 genome editing technique from the perspective of...
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| Format: | Article |
| Language: | Spanish |
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Universidad El Bosque
2020-06-01
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| Series: | Revista Colombiana de Bioética |
| Subjects: | |
| Online Access: | https://revistas.unbosque.edu.co/index.php/RCB/article/view/2732/2390 |
| _version_ | 1818515516121153536 |
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| author | Henry David Caro-Romero |
| author_facet | Henry David Caro-Romero |
| author_sort | Henry David Caro-Romero |
| collection | DOAJ |
| description | Purpose/Context. This article seeks to understand the meaning that the possibility of making genetic changes in human beings before birth would have for a group of individuals residing in Bogotá. The study focuses on the application of the CRISPR-Cas9 genome editing technique from the perspective of the bioethical principle of beneficence, i.e., to do the greatest good possible.
Method/Approach. First, the CRISPR-Cas9 technique and the bioethical principle of beneficence are theoretically reviewed. Then, international regulatory documents on genome editing are examined. Based on this, a video-based survey is administered to find out the hypothetical decision that a group of lay professionals would make on bioethical issues compared to a group of university students who have received bioethical training.
Results/Findings. Genome editing intended for prevention or therapy was approved by both groups, although with differences. Genome improvement was generally rejected for being immoral. However, both groups were open to accepting it but only as genome preparation for future generations due to the effects of climate change.
Discussion/Conclusions/Contributions. The bioethical principle of beneficence is insightful as it suggests both the private and common good. Moral reservations over heritable genome editing are also corroborated. |
| first_indexed | 2024-12-11T00:29:50Z |
| format | Article |
| id | doaj.art-bd806301d8894f17a5fccaee328a374a |
| institution | Directory Open Access Journal |
| issn | 2590-9452 |
| language | Spanish |
| last_indexed | 2024-12-11T00:29:50Z |
| publishDate | 2020-06-01 |
| publisher | Universidad El Bosque |
| record_format | Article |
| series | Revista Colombiana de Bioética |
| spelling | doaj.art-bd806301d8894f17a5fccaee328a374a2022-12-22T01:27:23ZspaUniversidad El BosqueRevista Colombiana de Bioética2590-94522020-06-01151117https://doi.org/10.18270/rcb.v15i1.2732Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of BeneficenceHenry David Caro-Romero0https://orcid.org/0000-0003-3848-2271Universidad Pedagógica NacionalPurpose/Context. This article seeks to understand the meaning that the possibility of making genetic changes in human beings before birth would have for a group of individuals residing in Bogotá. The study focuses on the application of the CRISPR-Cas9 genome editing technique from the perspective of the bioethical principle of beneficence, i.e., to do the greatest good possible. Method/Approach. First, the CRISPR-Cas9 technique and the bioethical principle of beneficence are theoretically reviewed. Then, international regulatory documents on genome editing are examined. Based on this, a video-based survey is administered to find out the hypothetical decision that a group of lay professionals would make on bioethical issues compared to a group of university students who have received bioethical training. Results/Findings. Genome editing intended for prevention or therapy was approved by both groups, although with differences. Genome improvement was generally rejected for being immoral. However, both groups were open to accepting it but only as genome preparation for future generations due to the effects of climate change. Discussion/Conclusions/Contributions. The bioethical principle of beneficence is insightful as it suggests both the private and common good. Moral reservations over heritable genome editing are also corroborated.https://revistas.unbosque.edu.co/index.php/RCB/article/view/2732/2390crispr-cas9preventive genomicsgene therapygenome improvementbioethical principle of beneficence |
| spellingShingle | Henry David Caro-Romero Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence Revista Colombiana de Bioética crispr-cas9 preventive genomics gene therapy genome improvement bioethical principle of beneficence |
| title | Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence |
| title_full | Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence |
| title_fullStr | Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence |
| title_full_unstemmed | Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence |
| title_short | Heritable Genome Editing: An Exploratory Study from the Bioethical Principle of Beneficence |
| title_sort | heritable genome editing an exploratory study from the bioethical principle of beneficence |
| topic | crispr-cas9 preventive genomics gene therapy genome improvement bioethical principle of beneficence |
| url | https://revistas.unbosque.edu.co/index.php/RCB/article/view/2732/2390 |
| work_keys_str_mv | AT henrydavidcaroromero heritablegenomeeditinganexploratorystudyfromthebioethicalprincipleofbeneficence |