Strontium Binding to α-Parvalbumin, a Canonical Calcium-Binding Protein of the “EF-Hand” Family

Strontium Binding to α-Parvalbumin, a Canonical Calcium-Binding Protein of the “EF-Hand” Family

Strontium salts are used for treatment of osteoporosis and bone cancer, but their impact on calcium-mediated physiological processes remains obscure. To explore Sr<sup>2+</sup> interference with Ca<sup>2+</sup> binding to proteins of the EF-hand family, we studied Sr<sup&g...

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Bibliographic Details
Main Authors: Alisa A. Vologzhannikova, Marina P. Shevelyova, Alexey S. Kazakov, Andrey S. Sokolov, Nadezhda I. Borisova, Eugene A. Permyakov, Nikoleta Kircheva, Valya Nikolova, Todor Dudev, Sergei E. Permyakov
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
metal selectivity
calcium-binding proteins
EF-hand
parvalbumin
protein structure
protein stability
Online Access:https://www.mdpi.com/2218-273X/11/8/1158

Internet

https://www.mdpi.com/2218-273X/11/8/1158

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