Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism
We discuss a case of primary hyperparathyroidism caused by a giant cystic parathyroid adenoma presenting with neck swelling and hypercalcemic crisis. Fine-needle aspiration cytology of presumed thyroid swelling from one of the two sites aspirated yielded clear fluid but was not attributed to parathy...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=4;spage=487;epage=490;aulast=Sumana |
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| author | B S Sumana M Sabaretnam Vijaya Sarathi Akshatha Savith |
| author_facet | B S Sumana M Sabaretnam Vijaya Sarathi Akshatha Savith |
| author_sort | B S Sumana |
| collection | DOAJ |
| description | We discuss a case of primary hyperparathyroidism caused by a giant cystic parathyroid adenoma presenting with neck swelling and hypercalcemic crisis. Fine-needle aspiration cytology of presumed thyroid swelling from one of the two sites aspirated yielded clear fluid but was not attributed to parathyroid pathology. Elevated serum calcium and intact parathormone (iPTH) levels suggested preoperative parathyroid pathology. Ultrasound neck and sestamibi scan for parathyroid localization were not conclusive. Due to resistant hypercalcemia, the patient underwent emergency bilateral neck exploration and excision of the identified left superior parathyroid cyst along with total thyroidectomy. Monitoring of intra-operative iPTH helped complete removal of hyperfunctioning parathyroid tissue. Histopathological examination confirmed the parathyroid cyst. Cystic parathyroid adenoma should be considered in the differential diagnosis of cystic neck lesions. |
| first_indexed | 2024-12-19T08:58:16Z |
| format | Article |
| id | doaj.art-bd87821e801e428fbce7dcbd5e00f78f |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-19T08:58:16Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-bd87821e801e428fbce7dcbd5e00f78f2022-12-21T20:28:34ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292015-01-0158448749010.4103/0377-4929.168847Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidismB S SumanaM SabaretnamVijaya SarathiAkshatha SavithWe discuss a case of primary hyperparathyroidism caused by a giant cystic parathyroid adenoma presenting with neck swelling and hypercalcemic crisis. Fine-needle aspiration cytology of presumed thyroid swelling from one of the two sites aspirated yielded clear fluid but was not attributed to parathyroid pathology. Elevated serum calcium and intact parathormone (iPTH) levels suggested preoperative parathyroid pathology. Ultrasound neck and sestamibi scan for parathyroid localization were not conclusive. Due to resistant hypercalcemia, the patient underwent emergency bilateral neck exploration and excision of the identified left superior parathyroid cyst along with total thyroidectomy. Monitoring of intra-operative iPTH helped complete removal of hyperfunctioning parathyroid tissue. Histopathological examination confirmed the parathyroid cyst. Cystic parathyroid adenoma should be considered in the differential diagnosis of cystic neck lesions.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=4;spage=487;epage=490;aulast=SumanaHypercalcemic crisisparathyroid adenomaparathyroid cystprimary hyperparathyroidism |
| spellingShingle | B S Sumana M Sabaretnam Vijaya Sarathi Akshatha Savith Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism Indian Journal of Pathology and Microbiology Hypercalcemic crisis parathyroid adenoma parathyroid cyst primary hyperparathyroidism |
| title | Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| title_full | Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| title_fullStr | Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| title_full_unstemmed | Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| title_short | Functional parathyroid cystic adenoma: A rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| title_sort | functional parathyroid cystic adenoma a rare cause of hypercalcemic crisis with primary hyperparathyroidism |
| topic | Hypercalcemic crisis parathyroid adenoma parathyroid cyst primary hyperparathyroidism |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=4;spage=487;epage=490;aulast=Sumana |
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