Polymyxin B and fusidic acid, a novel potent synergistic combination against Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance

Polymyxin B and fusidic acid, a novel potent synergistic combination against Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance

The increasing prevalence of multidrug-resistant (MDR) Gram-negative bacteria and comparatively limited options of antibiotics pose a major threat to public health worldwide. Polymyxin B is the last resort against extensively resistant Gram-negative bacterial infections. However, a large number of G...

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Bibliographic Details
Main Authors: Shuying Chen, Peiyao Zhou, Chunyang Wu, Jie Wang, Ying Zhou, Jiao Zhang, Bingjie Wang, Huilin Zhao, Lulin Rao, Meilan Li, Fangyou Yu, Chunchan Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
polymyxin B
fusidic acid
Klebsiella pneumoniae
resistance
synergistic effect
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1220683/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1220683/full

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