A rare case of familial reactive perforating collagenosis
Reactive perforating collagenosis (RPC) is a rare disorder of transepidermal elimination in which genetically altered collagen is extruded out through the epidermis. This disease usually starts as asymptomatic or pruritic umbilicated papules on extensor aspects of extremities and face, and the lesio...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
|
| Series: | Indian Journal of Paediatric Dermatology |
| Subjects: | |
| Online Access: | http://www.ijpd.in/article.asp?issn=2319-7250;year=2017;volume=18;issue=3;spage=230;epage=233;aulast=Tiwary |
| _version_ | 1828403859579469824 |
|---|---|
| author | Anup Kumar Tiwary Dharmendra K Mishra Shyam S Chaudhary |
| author_facet | Anup Kumar Tiwary Dharmendra K Mishra Shyam S Chaudhary |
| author_sort | Anup Kumar Tiwary |
| collection | DOAJ |
| description | Reactive perforating collagenosis (RPC) is a rare disorder of transepidermal elimination in which genetically altered collagen is extruded out through the epidermis. This disease usually starts as asymptomatic or pruritic umbilicated papules on extensor aspects of extremities and face, and the lesions become more conspicuous with age. It has two forms: Acquired and inherited form, of which inherited form is extremely rare. Here, we document a case of inherited form of RPC in a 13-year-old boy having multiple asymptomatic hyperpigmented umbilicated papules with a central keratotic plug distributed chiefly over face and extensor aspect of upper and lower extremities since his infancy, with history of similar lesions in his 18-year-old elder brother. |
| first_indexed | 2024-12-10T10:26:02Z |
| format | Article |
| id | doaj.art-bd90f205376a4e46b9b2404578449088 |
| institution | Directory Open Access Journal |
| issn | 2319-7250 |
| language | English |
| last_indexed | 2024-12-10T10:26:02Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Paediatric Dermatology |
| spelling | doaj.art-bd90f205376a4e46b9b24045784490882022-12-22T01:52:44ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502017-01-0118323023310.4103/2319-7250.184436A rare case of familial reactive perforating collagenosisAnup Kumar TiwaryDharmendra K MishraShyam S ChaudharyReactive perforating collagenosis (RPC) is a rare disorder of transepidermal elimination in which genetically altered collagen is extruded out through the epidermis. This disease usually starts as asymptomatic or pruritic umbilicated papules on extensor aspects of extremities and face, and the lesions become more conspicuous with age. It has two forms: Acquired and inherited form, of which inherited form is extremely rare. Here, we document a case of inherited form of RPC in a 13-year-old boy having multiple asymptomatic hyperpigmented umbilicated papules with a central keratotic plug distributed chiefly over face and extensor aspect of upper and lower extremities since his infancy, with history of similar lesions in his 18-year-old elder brother.http://www.ijpd.in/article.asp?issn=2319-7250;year=2017;volume=18;issue=3;spage=230;epage=233;aulast=TiwaryReactive perforating collagenosistransepidermal eliminationumbilicated |
| spellingShingle | Anup Kumar Tiwary Dharmendra K Mishra Shyam S Chaudhary A rare case of familial reactive perforating collagenosis Indian Journal of Paediatric Dermatology Reactive perforating collagenosis transepidermal elimination umbilicated |
| title | A rare case of familial reactive perforating collagenosis |
| title_full | A rare case of familial reactive perforating collagenosis |
| title_fullStr | A rare case of familial reactive perforating collagenosis |
| title_full_unstemmed | A rare case of familial reactive perforating collagenosis |
| title_short | A rare case of familial reactive perforating collagenosis |
| title_sort | rare case of familial reactive perforating collagenosis |
| topic | Reactive perforating collagenosis transepidermal elimination umbilicated |
| url | http://www.ijpd.in/article.asp?issn=2319-7250;year=2017;volume=18;issue=3;spage=230;epage=233;aulast=Tiwary |
| work_keys_str_mv | AT anupkumartiwary ararecaseoffamilialreactiveperforatingcollagenosis AT dharmendrakmishra ararecaseoffamilialreactiveperforatingcollagenosis AT shyamschaudhary ararecaseoffamilialreactiveperforatingcollagenosis AT anupkumartiwary rarecaseoffamilialreactiveperforatingcollagenosis AT dharmendrakmishra rarecaseoffamilialreactiveperforatingcollagenosis AT shyamschaudhary rarecaseoffamilialreactiveperforatingcollagenosis |