The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country
Background: Overall five-year survival rate of Wilm’s Tumor (WT) in developing countries is still poor. Delayed diagnosis is one of the contributing factors, whereas early diagnosis is an important thing for the outcome. It is caused by the WT burden in developing countries that was not comparable w...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2021-07-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1237 |
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| author | Aulia Rahmani Nur Melani Sari Vita Indriasari |
| author_facet | Aulia Rahmani Nur Melani Sari Vita Indriasari |
| author_sort | Aulia Rahmani |
| collection | DOAJ |
| description | Background: Overall five-year survival rate of Wilm’s Tumor (WT) in developing countries is still poor. Delayed diagnosis is one of the contributing factors, whereas early diagnosis is an important thing for the outcome. It is caused by the WT burden in developing countries that was not comparable with the number of facilities for diagnosis and treatment. Ultrasonography (USG) is the mandatory first-line imaging modality in children with a suspected abdominal mass and an overall sensitivity of76%. Additionally, it can be found in many health facilities at a lower cost, quick, non-invasive, and carries no risk of radiation. Therefore, the relationship between USG and histopathology should be measured.
Materials and Methods: A cross-sectional study with an analytical approach was performed in pediatric (0 untill 18 year of age) renal malignancy and neuroblastoma that admitted to Dr. Hasan Sadikin Hospital, Bandung between 2015-2018. Data were collected from medical records. Statistical analyses using Fisher exact test were done to determine the significance of the relationship between USG and histopathology.
Results: Forty-three samples were obtained based on inclusion criteria, such as WT (n=33), neuroblastoma (n=6), renal clear cell carcinoma (n=2), and no specific type of renal malignancy (n=2). Fisher exact test revealed the no-significant relationship between USG and histopathology with a p-value > 0.05
Conclusion: There is no significant relationship between USG and histopathology. Therefore, centralized unity for USG interpretation is recommended. |
| first_indexed | 2024-03-12T06:43:33Z |
| format | Article |
| id | doaj.art-bd92dc04f2e64dd9a976ce26119e015c |
| institution | Directory Open Access Journal |
| issn | 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T06:43:33Z |
| publishDate | 2021-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-bd92dc04f2e64dd9a976ce26119e015c2023-09-03T00:47:43ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072021-07-0115310.18502/ijhoscr.v15i3.6844The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing CountryAulia Rahmani0Nur Melani Sari1Vita Indriasari2Universitas PadjadjaranDepartement of Pediatrics, Hematology & Oncology Division, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Hospital, Bandung, IndonesiaDepartement of Pediatric Surgery, Faculty of Medicine, Universitas Padjadjaran/ Dr. Hasan Sadikin General Hospital, Bandung, IndonesiaBackground: Overall five-year survival rate of Wilm’s Tumor (WT) in developing countries is still poor. Delayed diagnosis is one of the contributing factors, whereas early diagnosis is an important thing for the outcome. It is caused by the WT burden in developing countries that was not comparable with the number of facilities for diagnosis and treatment. Ultrasonography (USG) is the mandatory first-line imaging modality in children with a suspected abdominal mass and an overall sensitivity of76%. Additionally, it can be found in many health facilities at a lower cost, quick, non-invasive, and carries no risk of radiation. Therefore, the relationship between USG and histopathology should be measured. Materials and Methods: A cross-sectional study with an analytical approach was performed in pediatric (0 untill 18 year of age) renal malignancy and neuroblastoma that admitted to Dr. Hasan Sadikin Hospital, Bandung between 2015-2018. Data were collected from medical records. Statistical analyses using Fisher exact test were done to determine the significance of the relationship between USG and histopathology. Results: Forty-three samples were obtained based on inclusion criteria, such as WT (n=33), neuroblastoma (n=6), renal clear cell carcinoma (n=2), and no specific type of renal malignancy (n=2). Fisher exact test revealed the no-significant relationship between USG and histopathology with a p-value > 0.05 Conclusion: There is no significant relationship between USG and histopathology. Therefore, centralized unity for USG interpretation is recommended.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1237Wilms tumor (WT); Ultrasonography (USG); Histopathology |
| spellingShingle | Aulia Rahmani Nur Melani Sari Vita Indriasari The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country International Journal of Hematology-Oncology and Stem Cell Research Wilms tumor (WT); Ultrasonography (USG); Histopathology |
| title | The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country |
| title_full | The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country |
| title_fullStr | The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country |
| title_full_unstemmed | The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country |
| title_short | The Role of Ultrasonography for Diagnosing Wilms Tumor in Developing Country |
| title_sort | role of ultrasonography for diagnosing wilms tumor in developing country |
| topic | Wilms tumor (WT); Ultrasonography (USG); Histopathology |
| url | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1237 |
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