An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran
Abstract The COVID-19 outbreak affected mental health globally. One of the major concerns following the COVID-19 pandemic was increased incidence of risky behaviors including alcohol consumption. This study evaluates the trend of alcohol poisoning in Loghman-Hakim Hospital (LHH), the main referral c...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-14799-2 |
| _version_ | 1811334334634786816 |
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| author | Seyed Kaveh Hadeiy Nasim Zamani Rebecca McDonald Omidvar Rezaei Ali-Asghar Kolahi Narges Gholami Fariba Farnaghi Hossein Hassanian-Moghaddam |
| author_facet | Seyed Kaveh Hadeiy Nasim Zamani Rebecca McDonald Omidvar Rezaei Ali-Asghar Kolahi Narges Gholami Fariba Farnaghi Hossein Hassanian-Moghaddam |
| author_sort | Seyed Kaveh Hadeiy |
| collection | DOAJ |
| description | Abstract The COVID-19 outbreak affected mental health globally. One of the major concerns following the COVID-19 pandemic was increased incidence of risky behaviors including alcohol consumption. This study evaluates the trend of alcohol poisoning in Loghman-Hakim Hospital (LHH), the main referral center of poisoning in Tehran, during the 2-year period from 1 year prior to 1 year after the onset (February 23rd, 2020) of the COVID-19 epidemic in Iran. All patients admitted with alcohol intoxication from February 23rd, 2019 to February 22nd, 2021 were evaluated and patient data extracted from LHH electronic hospital records. Alcohols were categorized as toxic (methyl alcohol) and non-toxic (ethyl alcohol). Of 2483 patients admitted, 796/14,493 (5.49%) and 1687/13,883 (12.15%) had been hospitalized before and after the onset of the COVID-19 epidemic in Iran, respectively. In total, 140 patients did not survive, of whom 131 (93.6%) were confirmed to have methanol intoxication. Mortality was significantly higher during the outbreak (127 vs 13; P < 0.001; OR: 4.90; CI 95%: 2.75 to 8.73). Among the patients, 503 were younger than age 20. Trend of alcohol intoxication showed increases in children (57 vs 17) and adolescents (246 vs 183) when compared before and after the COVID-19 epidemic outbreak. A total of 955 patients were diagnosed with methanol toxicity which occurred more frequently during the COVID-19 era (877 vs 78; P < 0.001; OR: 10.00; CI 95%: 7.75 to12.82). Interrupted time series analysis (April 2016–February 2021) showed that in the first month of the COVID-19 epidemic (March 2020), there was a significant increase in the alcohol intoxication rate by 13.76% (P < 0.02, CI = [2.42–24.91]). The trend of alcohol intoxication as well as resulting mortality increased in all age groups during the COVID-19 epidemic in Iran, indicating urgent need for the prevention of high-risk alcohol use as well as improved treatment. |
| first_indexed | 2024-04-13T17:06:27Z |
| format | Article |
| id | doaj.art-bd96608b27be4f86983d993bc41964b9 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T17:06:27Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-bd96608b27be4f86983d993bc41964b92022-12-22T02:38:27ZengNature PortfolioScientific Reports2045-23222022-06-0112111010.1038/s41598-022-14799-2An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, IranSeyed Kaveh Hadeiy0Nasim Zamani1Rebecca McDonald2Omidvar Rezaei3Ali-Asghar Kolahi4Narges Gholami5Fariba Farnaghi6Hossein Hassanian-Moghaddam7School of Medicine, Shahid Beheshti University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesSERAF, Norwegian Centre for Addiction Research, University of OsloDepartment of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesDepartment of Pediatrics, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical SciencesDepartment of Pediatrics, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical SciencesSocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesAbstract The COVID-19 outbreak affected mental health globally. One of the major concerns following the COVID-19 pandemic was increased incidence of risky behaviors including alcohol consumption. This study evaluates the trend of alcohol poisoning in Loghman-Hakim Hospital (LHH), the main referral center of poisoning in Tehran, during the 2-year period from 1 year prior to 1 year after the onset (February 23rd, 2020) of the COVID-19 epidemic in Iran. All patients admitted with alcohol intoxication from February 23rd, 2019 to February 22nd, 2021 were evaluated and patient data extracted from LHH electronic hospital records. Alcohols were categorized as toxic (methyl alcohol) and non-toxic (ethyl alcohol). Of 2483 patients admitted, 796/14,493 (5.49%) and 1687/13,883 (12.15%) had been hospitalized before and after the onset of the COVID-19 epidemic in Iran, respectively. In total, 140 patients did not survive, of whom 131 (93.6%) were confirmed to have methanol intoxication. Mortality was significantly higher during the outbreak (127 vs 13; P < 0.001; OR: 4.90; CI 95%: 2.75 to 8.73). Among the patients, 503 were younger than age 20. Trend of alcohol intoxication showed increases in children (57 vs 17) and adolescents (246 vs 183) when compared before and after the COVID-19 epidemic outbreak. A total of 955 patients were diagnosed with methanol toxicity which occurred more frequently during the COVID-19 era (877 vs 78; P < 0.001; OR: 10.00; CI 95%: 7.75 to12.82). Interrupted time series analysis (April 2016–February 2021) showed that in the first month of the COVID-19 epidemic (March 2020), there was a significant increase in the alcohol intoxication rate by 13.76% (P < 0.02, CI = [2.42–24.91]). The trend of alcohol intoxication as well as resulting mortality increased in all age groups during the COVID-19 epidemic in Iran, indicating urgent need for the prevention of high-risk alcohol use as well as improved treatment.https://doi.org/10.1038/s41598-022-14799-2 |
| spellingShingle | Seyed Kaveh Hadeiy Nasim Zamani Rebecca McDonald Omidvar Rezaei Ali-Asghar Kolahi Narges Gholami Fariba Farnaghi Hossein Hassanian-Moghaddam An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran Scientific Reports |
| title | An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran |
| title_full | An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran |
| title_fullStr | An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran |
| title_full_unstemmed | An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran |
| title_short | An interrupted time series analysis of hospital admissions due to alcohol intoxication during the COVID‐19 pandemic in Tehran, Iran |
| title_sort | interrupted time series analysis of hospital admissions due to alcohol intoxication during the covid 19 pandemic in tehran iran |
| url | https://doi.org/10.1038/s41598-022-14799-2 |
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