New Anti-Cancer Strategy to Suppress Colorectal Cancer Growth Through Inhibition of ATG4B and Lysosome Function
Autophagy inhibition has been proposed to be a potential therapeutic strategy for cancer, however, few autophagy inhibitors have been developed. Recent studies have indicated that lysosome and autophagy related 4B cysteine peptidase (ATG4B) are two promising targets in autophagy for cancer therapy....
Main Authors: | Yuanyuan Fu, Qianqian Gu, Li Luo, Jiecheng Xu, Yuping Luo, Fan Xia, Fanghai Han, Liang Hong, Xiao-Ming Yin, Zhiying Huang, Min Li |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/6/1523 |
Similar Items
-
Targeting ATG4 in Cancer Therapy
by: Yuanyuan Fu, et al.
Published: (2019-05-01) -
<i>Xanthium strumarium</i> Fruit Extract Inhibits ATG4B and Diminishes the Proliferation and Metastatic Characteristics of Colorectal Cancer Cells
by: Hsueh-Wei Chang, et al.
Published: (2019-06-01) -
Clinicopathological Association of Autophagy Related 5 Protein with Prognosis of Colorectal Cancer
by: Wan-Hsiang Hu, et al.
Published: (2021-04-01) -
Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation
by: Zhao-Qian Pan, et al.
Published: (2020-09-01) -
Natural Compounds Targeting the Autophagy Pathway in the Treatment of Colorectal Cancer
by: Yin-Xiao Du, et al.
Published: (2023-04-01)