Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients

Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients. Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this...

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Main Authors: N. Sargolzaee, HR. Arab, A. Moeintaghavi, M. Radvar
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2008-09-01
Series:Frontiers in Dentistry
Subjects:
Online Access:https://jdt.tums.ac.ir/index.php/jdt/article/view/157
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author N. Sargolzaee
HR. Arab
A. Moeintaghavi
M. Radvar
author_facet N. Sargolzaee
HR. Arab
A. Moeintaghavi
M. Radvar
author_sort N. Sargolzaee
collection DOAJ
description Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients. Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. Half of them were HTLV-1 carriers and the others were in HTLV-1 associated myelopathy tropical spastic paraparesia (HAM/TSP) stage.Subgingival dental plaque samples were taken using sterile paper points and examined to detect HTLV-1 using polymerase chain reaction (PCR). Results: None of the carrier stage patients revealed HTLV-1 virus, while only one patient in the HAM/TSP group was found with the virus. Conclusion: This study showed that the existence of HTLV-1 virus in subgingival plaque of patients suffering from HTLV-1 in carrier and HAM/TSP stages with healthy periodon-tium is rare. Studies with larger samples are recommended.
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spelling doaj.art-bd9fca4a3aeb4cd9b0a8ba49b4e7f27a2022-12-22T03:20:39ZengTehran University of Medical SciencesFrontiers in Dentistry2676-296X2008-09-0153Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients N. Sargolzaee0 HR. Arab1 A. Moeintaghavi2 M. Radvar3Associate Professor, Department of Periodontics, School of Dentistry, Mashhad University of Medical Associate Professor, Department of Periodontics, School of Dentistry, Mashhad University of Medical Associate Professor, Department of Periodontics, School of Dentistry, Mashhad University of Medical Associate Professor, Department of Periodontics, School of Dentistry, Mashhad University of Medical Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients. Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. Half of them were HTLV-1 carriers and the others were in HTLV-1 associated myelopathy tropical spastic paraparesia (HAM/TSP) stage.Subgingival dental plaque samples were taken using sterile paper points and examined to detect HTLV-1 using polymerase chain reaction (PCR). Results: None of the carrier stage patients revealed HTLV-1 virus, while only one patient in the HAM/TSP group was found with the virus. Conclusion: This study showed that the existence of HTLV-1 virus in subgingival plaque of patients suffering from HTLV-1 in carrier and HAM/TSP stages with healthy periodon-tium is rare. Studies with larger samples are recommended.https://jdt.tums.ac.ir/index.php/jdt/article/view/157Human T-lymphotropic virus 1Dental PlaquePolymerase Chain Reaction
spellingShingle N. Sargolzaee
HR. Arab
A. Moeintaghavi
M. Radvar
Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
Frontiers in Dentistry
Human T-lymphotropic virus 1
Dental Plaque
Polymerase Chain Reaction
title Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
title_full Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
title_fullStr Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
title_full_unstemmed Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
title_short Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
title_sort evaluation of htlv 1 in human subgingival plaque of seropositive patients
topic Human T-lymphotropic virus 1
Dental Plaque
Polymerase Chain Reaction
url https://jdt.tums.ac.ir/index.php/jdt/article/view/157
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AT hrarab evaluationofhtlv1inhumansubgingivalplaqueofseropositivepatients
AT amoeintaghavi evaluationofhtlv1inhumansubgingivalplaqueofseropositivepatients
AT mradvar evaluationofhtlv1inhumansubgingivalplaqueofseropositivepatients