Metabolome- and genome-scale model analyses for engineering of Aureobasidium pullulans to enhance polymalic acid and malic acid production from sugarcane molasses

Metabolome- and genome-scale model analyses for engineering of Aureobasidium pullulans to enhance polymalic acid and malic acid production from sugarcane molasses

Abstract Background Polymalic acid (PMA) is a water-soluble biopolymer with many attractive properties for food and pharmaceutical applications mainly produced by the yeast-like fungus Aureobasidium pullulans. Acid hydrolysis of PMA, resulting in release of the monomer l-malic acid (MA), which is wi...

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Bibliographic Details
Main Authors: Jun Feng, Jing Yang, Wenwen Yang, Jie Chen, Min Jiang, Xiang Zou
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Biotechnology for Biofuels
Subjects:
Aureobasidium pullulans
Metabolic engineering
Polymalic acid
Pyruvate carboxylase
Sugarcane molasses
Online Access:http://link.springer.com/article/10.1186/s13068-018-1099-7

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