Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic

Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic

Understanding the emergence of novel viruses requires an accurate and comprehensive annotation of their genomes. Overlapping genes (OLGs) are common in viruses and have been associated with pandemics but are still widely overlooked. We identify and characterize ORF3d, a novel OLG in SARS-CoV-2 that...

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Bibliographic Details
Main Authors: Chase W Nelson, Zachary Ardern, Tony L Goldberg, Chen Meng, Chen-Hao Kuo, Christina Ludwig, Sergios-Orestis Kolokotronis, Xinzhu Wei
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
genome annotation
natural selection
ORF3d
overlapping genes
pandemic
SARS-CoV-2
Online Access:https://elifesciences.org/articles/59633

Internet

https://elifesciences.org/articles/59633

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