Dramatic Tumor Shrinkage of Locally Advanced and Inoperable Adenoid Cystic Carcinoma after Intra-arterial Chemotherapy

Adenoid cystic carcinoma is rare and usually arises in the salivary glands. It grows slowly, but is characterized by easy perineural invasion with local infiltration and distant metastasis. In metastatic setting, the efficacy of intravenous chemotherapy is limited. Herein, we report one male patient...

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Bibliographic Details
Main Authors: Fu-Jen Hsueh, Huai-Cheng Huang, Ruey-Long Hong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-06-01
Series:Journal of Cancer Research and Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2311300616300714
Description
Summary:Adenoid cystic carcinoma is rare and usually arises in the salivary glands. It grows slowly, but is characterized by easy perineural invasion with local infiltration and distant metastasis. In metastatic setting, the efficacy of intravenous chemotherapy is limited. Herein, we report one male patient who had a advanced, inoperable adenoid cystic carcinoma with lung metastasis, presenting with right buccal unhealed ulcer, pain and poor intake, whose loco-regional tumors responded dramatically after intra-arterial chemotherapy and his symptoms were almost completely relieved. We also make a literature review for treatment of adenoid cystic carcinoma.
ISSN:2311-3006