Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Abstract Electrooxidation has emerged as an increasingly viable platform in molecular syntheses that can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical C−H activations, these arene functionalizations generally require directing groups to enable the C−H activati...

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Bibliographic Details
Main Authors: Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39747-0

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https://doi.org/10.1038/s41467-023-39747-0

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