Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification
Abstract Electrooxidation has emerged as an increasingly viable platform in molecular syntheses that can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical C−H activations, these arene functionalizations generally require directing groups to enable the C−H activati...
Main Authors: | Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-39747-0 |
Similar Items
-
Cobalt-catalyzed directed C–H alkenylation of pivalophenone N–H imine with alkenyl phosphates
by: Xu, Wengang, et al.
Published: (2018) -
Cobalt-catalyzed directed C–H alkenylation of pivalophenone N–H imine with alkenyl phosphates
by: Wengang Xu, et al.
Published: (2018-03-01) -
Palladium-catalyzed direct functionalization of benzoxazoles with alkenyl iodides
by: Gerelle, M, et al.
Published: (2012) -
Intramolecular palladium-catalyzed direct arylation of alkenyl triflates.
by: Cruz, A, et al.
Published: (2007) -
Site-selective electrochemical carboxylation of aromatic C(sp2)–H bonds with CO2
by: Rong Zhao, et al.
Published: (2023-01-01)