Neutrophil extracellular trap clearance by synovial macrophages in gout

Neutrophil extracellular trap clearance by synovial macrophages in gout

Abstract Background Monosodium urate (MSU) crystals, i.e., the central etiological factors in gouty arthritis, induce the formation of neutrophil extracellular traps (NETs). We investigated whether synovial macrophages could clear NETs as a self-resolution mechanism in acute gouty arthritis. Methods...

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Bibliographic Details
Main Authors: Ji Hye Jeong, Su Jin Choi, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Arthritis Research & Therapy
Subjects:
Monosodium urate crystals
Gout
Neutrophil extracellular traps
Efferocytosis
Online Access:https://doi.org/10.1186/s13075-021-02472-4

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