Conformational landscape of the yeast SAGA complex as revealed by cryo-EM
Abstract Spt-Ada-Gcn5-Acetyltransferase (SAGA) is a conserved multi-subunit complex that activates RNA polymerase II-mediated transcription by acetylating and deubiquitinating nucleosomal histones and by recruiting TATA box binding protein (TBP) to DNA. The prototypical yeast Saccharomyces cerevisia...
Main Authors: | Diana Vasyliuk, Joeseph Felt, Ellen D. Zhong, Bonnie Berger, Joseph H. Davis, Calvin K. Yip |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-16391-0 |
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