Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants
Although the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal growth. Accurate growth monitoring of preterm infant...
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| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/8/2841 |
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| author | Miheret Yitayew Nayef Chahin Salem Rustom Leroy R. Thacker Karen D. Hendricks-Muñoz |
| author_facet | Miheret Yitayew Nayef Chahin Salem Rustom Leroy R. Thacker Karen D. Hendricks-Muñoz |
| author_sort | Miheret Yitayew |
| collection | DOAJ |
| description | Although the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal growth. Accurate growth monitoring of preterm infants is critical in guiding nutritional protocols. Currently, there is no consensus regarding which growth assessment tool is suitable for monitoring postnatal growth of preterm infants to foster optimal neurodevelopmental outcomes while avoiding future consequences of aggressive nutritional approaches including increased risk for cardiovascular disease and metabolic syndrome. A retrospective single center cohort study was conducted to compare the performance of two growth-assessment tools, Fenton and Intergrowth-21st (IG-21st) in the classification of size at birth, identification of impaired growth and predicting neurodevelopment. A total of 340 infants with mean gestational age of 30 weeks were included. Proportion of agreement between the two tools for identification of small for gestational age (SGA) was high 0.94 (0.87, 0.1) however, agreement for classification of postnatal growth failure at discharge was moderate 0.6 (0.52, 0.69). Growth failure at discharge was less prevalent using IG-21st. There was significant association between weight-based growth failure and poor neurodevelopmental outcomes at 12 and 24 months of age. |
| first_indexed | 2024-03-10T08:30:32Z |
| format | Article |
| id | doaj.art-bdb0ade8b55047eaadc7790b8b2a5caf |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T08:30:32Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-bdb0ade8b55047eaadc7790b8b2a5caf2023-11-22T09:06:55ZengMDPI AGNutrients2072-66432021-08-01138284110.3390/nu13082841Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm InfantsMiheret Yitayew0Nayef Chahin1Salem Rustom2Leroy R. Thacker3Karen D. Hendricks-Muñoz4Department of Pediatrics, Children’s Hospital of Richmond, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Pediatrics, Children’s Hospital of Richmond, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Pediatrics, Children’s Hospital of Richmond, Virginia Commonwealth University, Richmond, VA 23298, USAAlthough the survival rate of preterm infants has improved over the years, growth failure and associated impaired neurodevelopmental outcome remains a significant morbidity. Optimal nutrition plays an important role in achieving adequate postnatal growth. Accurate growth monitoring of preterm infants is critical in guiding nutritional protocols. Currently, there is no consensus regarding which growth assessment tool is suitable for monitoring postnatal growth of preterm infants to foster optimal neurodevelopmental outcomes while avoiding future consequences of aggressive nutritional approaches including increased risk for cardiovascular disease and metabolic syndrome. A retrospective single center cohort study was conducted to compare the performance of two growth-assessment tools, Fenton and Intergrowth-21st (IG-21st) in the classification of size at birth, identification of impaired growth and predicting neurodevelopment. A total of 340 infants with mean gestational age of 30 weeks were included. Proportion of agreement between the two tools for identification of small for gestational age (SGA) was high 0.94 (0.87, 0.1) however, agreement for classification of postnatal growth failure at discharge was moderate 0.6 (0.52, 0.69). Growth failure at discharge was less prevalent using IG-21st. There was significant association between weight-based growth failure and poor neurodevelopmental outcomes at 12 and 24 months of age.https://www.mdpi.com/2072-6643/13/8/2841preterm infantgrowth curveintergrowthFentongrowth failureneurodevelopment |
| spellingShingle | Miheret Yitayew Nayef Chahin Salem Rustom Leroy R. Thacker Karen D. Hendricks-Muñoz Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants Nutrients preterm infant growth curve intergrowth Fenton growth failure neurodevelopment |
| title | Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants |
| title_full | Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants |
| title_fullStr | Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants |
| title_full_unstemmed | Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants |
| title_short | Fenton vs. Intergrowth-21st: Postnatal Growth Assessment and Prediction of Neurodevelopment in Preterm Infants |
| title_sort | fenton vs intergrowth 21st postnatal growth assessment and prediction of neurodevelopment in preterm infants |
| topic | preterm infant growth curve intergrowth Fenton growth failure neurodevelopment |
| url | https://www.mdpi.com/2072-6643/13/8/2841 |
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