Essential function of transmembrane transcription factor MYRF in promoting transcription of miRNA lin-4 during C. elegans development

Precise developmental timing control is essential for organism formation and function, but its mechanisms are unclear. In C. elegans, the microRNA lin-4 critically regulates developmental timing by post-transcriptionally downregulating the larval-stage-fate controller LIN-14. However, the mechanisms...

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Bibliographic Details
Main Authors: Zhimin Xu, Zhao Wang, Lifang Wang, Yingchuan B Qi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89903