S1PR1/S1PR3-YAP signaling and S1P-ALOX15 signaling contribute to an aggressive behavior in obesity-lymphoma
Highlights • Obesity negatively impacted progression-free survival and overall survival in lymphoma patients while an aggressive tumor growth pattern was found in obesity-lymphoma mice. • S1P-S1PR1/S1PR3-YAP signaling mediated lymphomagenesis contributing to tumor aggressive growth in obesity-lympho...
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Bibliographic Details
| Main Authors: |
Xingtong Wang,
Wei Guo,
Xiaoju Shi,
Yujia Chen,
Youxi Yu,
Beibei Du,
Min Tan,
Li Tong,
Anna Wang,
Xianying Yin,
Jing Guo,
Robert C. Martin,
Ou Bai,
Yan Li |
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| Format: | Article
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| Language: | English |
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| Published: |
BMC
2023-01-01
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| Series: | Journal of Experimental & Clinical Cancer Research
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| Subjects: | |
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| Online Access: | https://doi.org/10.1186/s13046-022-02589-7
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