Toward a Value-Based Therapy Recommendation Model

Patient value is an important factor in clinical decision making, but conventionally, it is not incorporated in the decision processes. Clinical decision making has some clinical guidelines as a reference. There are very few value-based clinical guidelines, but knowledge about how values affect deci...

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Main Authors: Zhang Liu, Liang Xiao
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/11/16/2362
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author Zhang Liu
Liang Xiao
author_facet Zhang Liu
Liang Xiao
author_sort Zhang Liu
collection DOAJ
description Patient value is an important factor in clinical decision making, but conventionally, it is not incorporated in the decision processes. Clinical decision making has some clinical guidelines as a reference. There are very few value-based clinical guidelines, but knowledge about how values affect decision making is mentioned in some scattered studies in the literature. We use a literature review method to extract evidence and integrate it as part of the decision-making model. In this paper, a value-based therapy recommendation comprehensive model is proposed. A literature analysis is conducted to collect value-based evidence. The patients’ values are defined and classified with fine granularity. Categorized values and candidate therapies are used in combination as filtering keywords to build this literature database. The literature analysis method generates a literature database used as a source of arguments for influencing decision making based on values. Then, a formalism model is put forward to integrate the value-based evidence with clinical evidence, and the literature databases and clinical guidelines are collected and analyzed to populate the evidence repository. During the decision-making processes, the evidence repository is utilized to match patients’ clinical information and values. Decision-makers can dynamically adjust the relative importance of the two pieces of evidence to obtain a treatment plan that is more suitable for the patient. A prototype system was implemented using a case study for breast cancer and validated for feasibility and effectiveness through controlled experiments.
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spelling doaj.art-bdb3e040da214a9cb9af64971b42f6ea2023-11-19T01:20:00ZengMDPI AGHealthcare2227-90322023-08-011116236210.3390/healthcare11162362Toward a Value-Based Therapy Recommendation ModelZhang Liu0Liang Xiao1School of Computer Science, Hubei University of Technology, Wuhan 430068, ChinaSchool of Computer Science, Hubei University of Technology, Wuhan 430068, ChinaPatient value is an important factor in clinical decision making, but conventionally, it is not incorporated in the decision processes. Clinical decision making has some clinical guidelines as a reference. There are very few value-based clinical guidelines, but knowledge about how values affect decision making is mentioned in some scattered studies in the literature. We use a literature review method to extract evidence and integrate it as part of the decision-making model. In this paper, a value-based therapy recommendation comprehensive model is proposed. A literature analysis is conducted to collect value-based evidence. The patients’ values are defined and classified with fine granularity. Categorized values and candidate therapies are used in combination as filtering keywords to build this literature database. The literature analysis method generates a literature database used as a source of arguments for influencing decision making based on values. Then, a formalism model is put forward to integrate the value-based evidence with clinical evidence, and the literature databases and clinical guidelines are collected and analyzed to populate the evidence repository. During the decision-making processes, the evidence repository is utilized to match patients’ clinical information and values. Decision-makers can dynamically adjust the relative importance of the two pieces of evidence to obtain a treatment plan that is more suitable for the patient. A prototype system was implemented using a case study for breast cancer and validated for feasibility and effectiveness through controlled experiments.https://www.mdpi.com/2227-9032/11/16/2362patient valuesclinical decision makingpersonalized therapyrecommendation modelargumentation
spellingShingle Zhang Liu
Liang Xiao
Toward a Value-Based Therapy Recommendation Model
Healthcare
patient values
clinical decision making
personalized therapy
recommendation model
argumentation
title Toward a Value-Based Therapy Recommendation Model
title_full Toward a Value-Based Therapy Recommendation Model
title_fullStr Toward a Value-Based Therapy Recommendation Model
title_full_unstemmed Toward a Value-Based Therapy Recommendation Model
title_short Toward a Value-Based Therapy Recommendation Model
title_sort toward a value based therapy recommendation model
topic patient values
clinical decision making
personalized therapy
recommendation model
argumentation
url https://www.mdpi.com/2227-9032/11/16/2362
work_keys_str_mv AT zhangliu towardavaluebasedtherapyrecommendationmodel
AT liangxiao towardavaluebasedtherapyrecommendationmodel